Kannisto P, Ekblad E, Helm G, Owman C, Sjöberg N O, Stjernquist M, Sundler F, Walles B
Histochemistry. 1986;86(1):25-34. doi: 10.1007/BF00492342.
The immunocytochemical distribution of substance P (SP), gastrin releasing peptide (GRP), vasoactive intestinal polypeptide (VIP), peptide histidine isoleucine (PHI), and neuropeptide Y (NPY) was studied in the ovary and the Fallopian tube (oviduct) of rats, guinea-pigs, cows, pigs and humans. Generally, the nerve supply was better developed in the oviduct than in the ovary. GRP fibers were most scarce in all tissues. Nerves containing SP were particularly numerous in the oviduct of rat and guinea-pig, supplying the muscular wall and blood vessels. VIP and PHI coexisted in dense plexuses of nerves, not only around blood vessels but also in the follicular wall and the interstitial gland of the ovary, as well as within the smooth muscle layers and subepithelially in the oviduct. The general distribution of NPY was similar, but these immunoreactive nerves were even more numerous. Sequential staining for dopamine-beta-hydroxylase and NPY together with results of chemical sympathectomy with 6-hydroxydopamine suggested that NPY was stored in the noradrenergic sympathetic nerves.
研究了P物质（SP）、胃泌素释放肽（GRP）、血管活性肠肽（VIP）、肽组氨酸异亮氨酸（PHI）和神经肽Y（NPY）在大鼠、豚鼠、牛、猪和人类的卵巢及输卵管中的免疫细胞化学分布。一般来说，输卵管中的神经支配比卵巢中发育得更好。GRP纤维在所有组织中最为稀少。含SP的神经在大鼠和豚鼠的输卵管中特别多，分布于肌壁和血管。VIP和PHI共存于密集的神经丛中，不仅在血管周围，也在卵巢的卵泡壁和间质腺中，以及输卵管的平滑肌层内和上皮下。NPY的总体分布相似，但这些免疫反应性神经数量更多。多巴胺-β-羟化酶和NPY的连续染色以及用6-羟基多巴胺进行化学交感神经切除的结果表明，NPY储存在去甲肾上腺素能交感神经中。
