• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Editorial: Preclinical Animal Models and Measures of Pain: Improving Predictive Validity for Analgesic Drug Development.

作者信息

Tappe-Theodor Anke, Negus S Stevens, Martin Thomas J

机构信息

Institute of Pharmacology, University of Heidelberg, Heidelberg, Germany.

Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, United States.

出版信息

Front Pain Res (Lausanne). 2022 Mar 23;3:867786. doi: 10.3389/fpain.2022.867786. eCollection 2022.

DOI:10.3389/fpain.2022.867786
PMID:35399151
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8985925/
Abstract
摘要

相似文献

1
Editorial: Preclinical Animal Models and Measures of Pain: Improving Predictive Validity for Analgesic Drug Development.社论:临床前动物模型与疼痛测量:提高镇痛药研发的预测效度
Front Pain Res (Lausanne). 2022 Mar 23;3:867786. doi: 10.3389/fpain.2022.867786. eCollection 2022.
2
Improving the translation of analgesic drugs to the clinic: animal models of neuropathic pain.改善镇痛药在临床中的转化:神经病理性疼痛的动物模型。
Br J Pharmacol. 2014 Jun;171(12):2951-63. doi: 10.1111/bph.12645.
3
Face-to-face comparison of the predictive validity of two models of neuropathic pain in the rat: analgesic activity of pregabalin, tramadol and duloxetine.两种大鼠神经病理性疼痛模型预测有效性的面对面比较:普瑞巴林、曲马多和度洛西汀的镇痛活性。
Eur J Pharmacol. 2014 Jul 15;735:17-25. doi: 10.1016/j.ejphar.2014.04.003. Epub 2014 Apr 12.
4
Animal models of pain: Diversity and benefits.疼痛的动物模型:多样性与益处。
J Neurosci Methods. 2021 Jan 15;348:108997. doi: 10.1016/j.jneumeth.2020.108997. Epub 2020 Nov 11.
5
Giving priority to preclinical pain measures resistant to existing drugs for developing innovative analgesics.优先考虑对现有药物有抗性的临床前疼痛指标,以开发创新的镇痛药物。
Drug Dev Res. 2018 Jun;79(4):147-156. doi: 10.1002/ddr.21429. Epub 2018 May 6.
6
Neuropathic pain models in the development of analgesic drugs.用于镇痛药研发的神经病理性疼痛模型。
Scand J Pain. 2011 Oct 1;2(4):172-177. doi: 10.1016/j.sjpain.2011.06.003.
7
Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain.雷帕霉素酰胺在神经损伤和化疗诱导的神经性疼痛模型中的作用。
Eur J Pharmacol. 2018 Mar 15;823:27-34. doi: 10.1016/j.ejphar.2018.01.041. Epub 2018 Feb 4.
8
Challenges in translational drug research in neuropathic and inflammatory pain: the prerequisites for a new paradigm.神经性和炎性疼痛的转化药物研究中的挑战:新范式的先决条件
Eur J Clin Pharmacol. 2017 Oct;73(10):1219-1236. doi: 10.1007/s00228-017-2301-8. Epub 2017 Sep 11.
9
Predictive validity of pharmacologic interventions in animal models of neuropathic pain.药物干预在神经性疼痛动物模型中的预测效度
Scand J Pain. 2011 Oct 1;2(4):178-184. doi: 10.1016/j.sjpain.2011.06.002.
10
Animal models of chronic pain: Advances and challenges for clinical translation.慢性疼痛的动物模型:临床转化的进展与挑战
J Neurosci Res. 2017 Jun;95(6):1242-1256. doi: 10.1002/jnr.23768. Epub 2016 Jul 4.

引用本文的文献

1
Antinociceptive Effects of 2/3-Subtype-Selective GABA Receptor Positive Allosteric Modulators KRM-II-81 and NS16085 in Male Rats: Behavioral Specificity.2/3 型 GABA 受体正变构调节剂 KRM-II-81 和 NS16085 在雄性大鼠中的抗伤害作用:行为特异性。
J Pharmacol Exp Ther. 2024 Nov 19;391(3):389-398. doi: 10.1124/jpet.123.002070.
2
Combination Drug Therapy for the Management of Chronic Neuropathic Pain.联合药物治疗用于慢性神经性疼痛管理。
Biomolecules. 2023 Dec 16;13(12):1802. doi: 10.3390/biom13121802.

本文引用的文献

1
Core Outcome Measures in Preclinical Assessment of Candidate Analgesics.候选镇痛药临床前评估的核心结局指标。
Pharmacol Rev. 2019 Apr;71(2):225-266. doi: 10.1124/pr.118.017210.
2
Pros and Cons of Clinically Relevant Methods to Assess Pain in Rodents.临床相关方法评估啮齿类动物疼痛的优缺点。
Neurosci Biobehav Rev. 2019 May;100:335-343. doi: 10.1016/j.neubiorev.2019.03.009. Epub 2019 Mar 15.
3
Assessment of Behavioral Disruption in Rats with Abdominal Inflammation Using Visual Cue Titration and the Five-choice Serial-reaction Time Task.使用视觉线索滴定法和五选择连续反应时间任务评估腹部炎症大鼠的行为紊乱
Anesthesiology. 2017 Aug;127(2):372-381. doi: 10.1097/ALN.0000000000001702.
4
Assessment of Chronic Pain: Domains, Methods, and Mechanisms.慢性疼痛的评估:领域、方法与机制
J Pain. 2016 Sep;17(9 Suppl):T10-20. doi: 10.1016/j.jpain.2015.08.010.
5
Rationale and methods for assessment of pain-depressed behavior in preclinical assays of pain and analgesia.疼痛与镇痛临床前试验中疼痛-抑郁行为评估的原理与方法。
Methods Mol Biol. 2010;617:79-91. doi: 10.1007/978-1-60327-323-7_7.
6
Unmasking the tonic-aversive state in neuropathic pain.揭示神经性疼痛中的紧张性不适状态。
Nat Neurosci. 2009 Nov;12(11):1364-6. doi: 10.1038/nn.2407. Epub 2009 Sep 27.
7
Animal models of pain: progress and challenges.疼痛的动物模型:进展与挑战。
Nat Rev Neurosci. 2009 Apr;10(4):283-94. doi: 10.1038/nrn2606. Epub 2009 Mar 4.
8
Forebrain pain mechanisms.前脑疼痛机制。
Brain Res Rev. 2009 Apr;60(1):226-42. doi: 10.1016/j.brainresrev.2008.12.014. Epub 2008 Dec 31.
9
Evolution of pain theories.疼痛理论的演变。
Int Anesthesiol Clin. 1970 Spring;8(1):3-34. doi: 10.1097/00004311-197000810-00003.