Talati S, Mahadevan P R
Indian J Lepr. 1986 Jul-Sep;58(3):367-72.
Presence of lipase, in Mycobacterium leprae obtained from human nodules and infected armadillo tissues, has been detected by demonstrating the ability of the bacteria to hydrolyze tributyrin. This capacity is expressed during incubation of the bacteria with the substrate and needs a source of carbon and other energy metabolites. The activity is blocked by anti M. leprae drug rifampicin. It is concluded that expression of lipase activity is a metabolic event of M. leprae, while they are maintained in an energy providing medium.
从人结节和感染犰狳组织中获取的麻风分枝杆菌中，通过证明该细菌水解三丁酸甘油酯的能力检测到了脂肪酶的存在。这种能力在细菌与底物孵育期间表现出来，并且需要碳源和其他能量代谢物。该活性被抗麻风分枝杆菌药物利福平阻断。得出的结论是，脂肪酶活性的表达是麻风分枝杆菌在能量供应培养基中维持时的一种代谢事件。
