Department of Dermatology, Wuhan First Hospital, Wuhan 430022, Hubei, China.
Department of Dermatology, Hankou Hospital, Wuhan 430012, Hubei, China.
Comput Intell Neurosci. 2022 Mar 30;2022:9484230. doi: 10.1155/2022/9484230. eCollection 2022.
This study aimed to investigate the therapeutic effect of ephedra-forsythia-red bean decoction (a formula of traditional Chinese medicine) addition and subtraction treatment of psoriasis vulgaris based on 22 MHz high-frequency ultrasound, so as to provide reference for the selection of traditional Chinese medicine formulas for psoriasis and the clinical application of ultrasound. 80 patients with psoriasis vulgaris with exterior closing and internal depression syndrome diagnosed and treated in the hospital were divided into an observation group (40 cases) and a control group. Patients in the observation group were received ephedra-forsythia-red bean decoction addition and subtraction; and those in the control group were received traditional Chinese medicine of observation group subtraction of raw ephedra, cinnamomum cassia, addition of fineleaf schizonepeta herb, divaricate saposhnikovia root. 22 MHz high-frequency ultrasonography was also performed. The psoriasis area and severity index (PASI) score and efficacy indicators were compared between the two groups. The results showed that the detection rate of nail malnutrition and psoriasis infiltration in psoriasis by high-frequency ultrasound was significantly higher than that by arthroscopy, and the difference was significant ( < 0.05). The total PASI score of the two groups after treatment was significantly lower than that before treatment, and the total PASI score of the observation group was lower than that of the control group, and the difference was statistically significant ( < 0.05). The total effective rate of the observation group (87.5%) was significantly higher than that of the control group (67.5%), and the difference was statistically significant ( < 0.05). It was found that high-frequency ultrasound can effectively display the condition and prognosis of patients with psoriasis. Ephedra-forsythia-red bean decoction was an effective traditional Chinese medicine formula for the treatment of psoriasis vulgaris.
本研究旨在探讨基于 22MHz 高频超声的麻黄-连翘-赤小豆汤加减治疗寻常型银屑病的疗效，为银屑病的中药方剂选择及超声的临床应用提供参考。将医院诊治的 80 例外闭里郁型寻常型银屑病患者分为观察组（40 例）和对照组（40 例）。观察组患者接受麻黄-连翘-赤小豆汤加减治疗；对照组患者接受观察组中药减去生麻黄、肉桂，加入细叶败酱草、防风。同时进行 22MHz 高频超声检查。比较两组患者的银屑病面积和严重程度指数（PASI）评分和疗效指标。结果显示，高频超声对指甲营养不良和银屑病浸润的检出率明显高于关节镜检查，差异有统计学意义（<0.05）。两组治疗后的总 PASI 评分均明显低于治疗前，观察组的总 PASI 评分低于对照组，差异有统计学意义（<0.05）。观察组总有效率（87.5%）明显高于对照组（67.5%），差异有统计学意义（<0.05）。研究表明，高频超声能有效显示银屑病患者的病情及预后，麻黄-连翘-赤小豆汤是治疗寻常型银屑病的有效中药方剂。
