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颈椎脊髓损伤患者手术治疗的结果及其预后因素

Outcomes of Patients with Cervical Spinal Cord Injury Treated by Surgery and Their Prognostic Factors.

作者信息

Wu Xinfeng, Song Qingpeng, Jin Peihao, Liu Bo

机构信息

Department of Spine Surgery, Beijing Jishuitan Hospital, Beijing 100035, China.

出版信息

Appl Bionics Biomech. 2022 Mar 30;2022:8720290. doi: 10.1155/2022/8720290. eCollection 2022.

DOI:10.1155/2022/8720290
PMID:35401787
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8986444/
Abstract

OBJECTIVE

To investigate the outcomes of patients with cervical spinal cord injury treated by surgery and their prognostic factors.

METHODS

We retrospectively analyzed 139 patients with cervical spinal cord injury treated by surgery at our hospital, who were admitted between January 2017 and December 2018. Depending on the Barthel index at last follow-up, the patients were divided into the recovery group ( = 60, Barthel index > 45) and the nonrecovery group ( = 79, Barthel index ≤ 45). General information of patients in the two groups was compared. The significant factors were further introduced into the logistic regression model. The poor prognostic factors of cervical spinal cord injury treated by surgery were analyzed, and specific nursing measures were taken.

RESULTS

There were significant differences in the duration of injury before admission, duration of injury before surgery, transportation and protection before admission, spinal canal invasion rate, and hormonal therapy within 8 h after injury between the patients achieving good postoperative recovery and those not ( < 0.05). Logistic regression analysis showed that all the factors above were prognostic factors for cervical spinal cord injury treated surgically.

CONCLUSION

The duration of injury before admission, duration of injury before surgery, transportation and protection before admission, spinal canal invasion rate, and hormonal therapy within 8 h after injury were prognostic factors of patients with cervical spinal cord injury treated by surgery. The following factors should be considered for favorable outcomes: spinal protection during transportation to hospital, timely hormonal shock therapy to delay injury progression, and timely surgery to relieve pain. The spine is composed of cervical, thoracic, lumbar, sacral, and caudal vertebrae.

摘要

目的

探讨手术治疗颈脊髓损伤患者的疗效及其预后因素。

方法

回顾性分析2017年1月至2018年12月在我院接受手术治疗的139例颈脊髓损伤患者。根据末次随访时的Barthel指数,将患者分为恢复组(n = 60,Barthel指数>45)和未恢复组(n = 79,Barthel指数≤45)。比较两组患者的一般资料。将有统计学意义的因素进一步纳入Logistic回归模型。分析手术治疗颈脊髓损伤的不良预后因素,并采取针对性护理措施。

结果

术后恢复良好与未恢复的患者在入院前损伤时间、手术前损伤时间、入院前转运及保护情况、椎管侵占率、伤后8 h内激素治疗等方面比较,差异有统计学意义(P<0.05)。Logistic回归分析显示,上述因素均为手术治疗颈脊髓损伤的预后因素。

结论

入院前损伤时间、手术前损伤时间、入院前转运及保护情况、椎管侵占率、伤后8 h内激素治疗是手术治疗颈脊髓损伤患者的预后因素。为取得良好疗效,应考虑以下因素:转运至医院途中的脊柱保护、及时给予激素冲击治疗以延缓损伤进展、及时手术以缓解疼痛。脊柱由颈椎、胸椎、腰椎、骶椎和尾椎组成。

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Orthop Surg. 2023 Apr;15(4):1008-1020. doi: 10.1111/os.13679. Epub 2023 Feb 13.

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Neural Regen Res. 2022 Aug;17(8):1703-1710. doi: 10.4103/1673-5374.332203.
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Overview of the Spinal Cord Injury-Functional Index (SCI-FI): Structure and Recent Advances.脊髓损伤功能指数(SCI-FI)概述:结构与最新进展
Arch Phys Med Rehabil. 2022 Feb;103(2):185-190. doi: 10.1016/j.apmr.2021.10.006. Epub 2021 Oct 28.
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Spinal Cord Injury-Functional Index/Capacity: Responsiveness to Change Over Time.脊髓损伤功能指数/能力:随时间变化的反应性。
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Zhongguo Gu Shang. 2020 Feb 25;33(2):158-65. doi: 10.12200/j.issn.1003-0034.2020.02.014.
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The safety and feasibility of a new rehabilitation robotic exoskeleton for assisting individuals with lower extremity motor complete lesions following spinal cord injury (SCI): an observational study.一种新型康复机器人外骨骼用于辅助脊髓损伤(SCI)后下肢运动完全性损伤个体的安全性和可行性:一项观察性研究。
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Phrenic nerve neurotization utilizing half of the spinal accessory nerve to the functional restoration of the paralyzed diaphragm in high spinal cord injury secondary to brain tumor resection.利用副神经的一半进行膈神经神经化以恢复脑肿瘤切除术后高位脊髓损伤所致瘫痪膈肌的功能。
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Intracerebroventricular Delivery of Human Umbilical Cord Mesenchymal Stem Cells as a Promising Therapy for Repairing the Spinal Cord Injury Induced by Kainic Acid.脑室内注射人脐带间充质干细胞作为修复红藻氨酸诱导的脊髓损伤的一种有前途的治疗方法。
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