Singh Anita, Magee Rachel, Balasubramanian Sriram
Widener University, School of Engineering, Chester, Pennsylvania, USA.
Drexel University, School of Biomedical Engineering, Science and Health Systems, Philadelphia, Pennsylvania, USA.
Neurol Neurobiol (Tallinn). 2020;3(2). doi: 10.31487/j.nnb.2020.02.08. Epub 2020 May 28.
The response of neonatal spinal cord tissue to tensile loading is not well-studied. In this study, isolated fresh neonatal cervical spinal cord samples, obtained from twelve 2-4 days old piglets, were tested in uniaxial tension at a rate of 500 mm/min until failure. Maximum load, maximum stress, percentage strain at maximum stress and modulus of elasticity were reported to be 14.6±3.4 N, 0.34±0.11 MPa, 29.3±5.4% and 1.52±0.8 MPa, respectively. These data can help understand the biomechanical behavior of the spinal cord in neonates and can be further used in computational modeling to understand injury mechanisms better and help develop injury prevention strategies.
新生儿脊髓组织对拉伸负荷的反应尚未得到充分研究。在本研究中，从12只2 - 4日龄仔猪获取的新鲜离体新生儿颈段脊髓样本，以500毫米/分钟的速率进行单轴拉伸测试直至破坏。据报道，最大负荷、最大应力、最大应力时的应变百分比和弹性模量分别为14.6±3.4牛、0.34±0.11兆帕、29.3±5.4%和1.52±0.8兆帕。这些数据有助于了解新生儿脊髓的生物力学行为，并可进一步用于计算建模，以更好地理解损伤机制并帮助制定损伤预防策略。
