Bilston L E, Thibault L E
Department of Mechanical and Mechatronic Engineering, University of Sydney, Australia.
Ann Biomed Eng. 1996 Jan-Feb;24(1):67-74. doi: 10.1007/BF02770996.
The response of spinal cord tissue to mechanical loadings is not well understood. In this study, isolated fresh cervical spinal cord samples were obtained from cadavers at autopsy and tested in uniaxial tension at moderate strain rates. Stress relaxation experiments were performed with an applied strain rate and peak strain in the physiological range, similar to those seen in the spinal cord during voluntary motion. The spinal cord samples exhibited a nonlinear stress-strain response with increasing strain increasing the tangent modulus. In addition, significant relaxation was observed over 1 min. A quasilinear viscoelastic model was developed to describe the behavior of the spinal cord tissue and was found to describe the material behavior adequately. The data also were fitted to both hyperelastic and viscoelastic fluid models for comparison with other data in the literature.
脊髓组织对机械负荷的反应尚未得到充分了解。在本研究中，从尸体解剖时获取分离的新鲜颈段脊髓样本，并在中等应变速率下进行单轴拉伸测试。进行应力松弛实验时，施加的应变速率和峰值应变处于生理范围内，类似于脊髓在自主运动时所观察到的情况。脊髓样本呈现出非线性应力 - 应变响应，随着应变增加，切线模量增大。此外，在1分钟内观察到显著的松弛现象。开发了一个准线性粘弹性模型来描述脊髓组织的行为，发现该模型能够充分描述材料行为。还将数据拟合到超弹性和粘弹性流体模型，以便与文献中的其他数据进行比较。
