Papadopoulos Nestoras, Dzemali Omer, Bott Luisa, Ntinopoulos Vasileios, Miskovic Aleksandra, Moritz Anton
Department of Cardiac Surgery, Triemli Hospital, Zurich, Switzerland.
Department of Thoracic and Cardiovascular Surgery, Goethe University Frankfurt/Main, Germany.
JTCVS Tech. 2022 Jan 19;12:39-51. doi: 10.1016/j.xjtc.2022.01.005. eCollection 2022 Apr.
In the current study, we present our mid-term experience with modified edge-to-edge repair technique through a transventricular and transaortic route in patients requiring left ventricular remodeling or aortic root/valve surgery.
From December 2006 through April 2015, 49 high-risk patients (median age: 69 years; median European System for Cardiac Operative Risk Evaluation II: 11.4 [6.54-14.9]) underwent transventricular (N = 7; 14%) or transaortic (N = 42; 86%) edge-to-edge mitral valve repair. The Alfieri stitch technique was modified by MitraClip type overcorrection and solid buttressing behind the posterior leaflet. Indication was grade 2+ functional mitral valve incompetence and dilated or impaired left ventricle (N = 25; 52%), or grade 3+ (N = 22; 45%) and grade 4+ functional mitral valve regurgitation (N = 2; 4%). Surgical procedure included aortic root surgery in 65%, aortic valve replacement with surgical revascularization in 18%, and Dor-plasty with surgical revascularization in 14%.
Intraoperative mortality and early neurologic complications were absent in our series. Ninety-day mortality was 12.2% (N = 6). Median clinical and echocardiographic follow-up-time was 50.7 (21.5-44.1) and 39.2 (33.7-44.1) months, respectively. Median postoperative transvalvular gradient was low (2.72 [1.91-4.22] mm Hg) and did not increase during follow-up ( = .268), although peak gradient rose slightly from 7.41 to 8.12 mm Hg ( = .071). The actuarial reoperation free rate at the index valve was 96.8%.
Transventricular or transaortic Alfieri mitral repair mimicking mitral clip overcorrection represents a quick and safe technique in the setting of high-risk patients undergoing left ventricular remodeling or aortic root/valve surgery and can be performed with low risk of creating mitral stenosis at midterm. The technique is straightforward, with reliable identification of the center of the valve leaflets being the limitation.
在本研究中,我们介绍了通过经心室和经主动脉途径采用改良缘对缘修复技术治疗需要进行左心室重塑或主动脉根部/瓣膜手术患者的中期经验。
从2006年12月至2015年4月,49例高危患者(中位年龄:69岁;欧洲心脏手术风险评估系统II中位数:11.4[6.54 - 14.9])接受了经心室(n = 7;14%)或经主动脉(n = 42;86%)缘对缘二尖瓣修复术。Alfieri缝合技术通过MitraClip型过度矫正和在后叶后方进行坚实支撑来改良。适应症为2+级功能性二尖瓣反流以及扩张或功能受损的左心室(n = 25;52%),或3+级(n = 22;45%)和4+级功能性二尖瓣反流(n = 2;4%)。手术操作包括65%的主动脉根部手术、18%的主动脉瓣置换术联合外科血管重建以及14%的Dor成形术联合外科血管重建。
我们的系列研究中无术中死亡和早期神经系统并发症。90天死亡率为12.2%(n = 6)。临床和超声心动图随访时间中位数分别为50.7(21.5 - 44.1)个月和39.2(33.7 - 44.1)个月。术后跨瓣压差中位数较低(2.72[1.91 - 4.22]mmHg),且随访期间未增加(P = 0.268),尽管峰值压差从7.41mmHg略有上升至8.12mmHg(P = 0.071)。首次手术瓣膜的无再次手术率为96.8%。
模仿二尖瓣夹过度矫正的经心室或经主动脉Alfieri二尖瓣修复术是一种快速且安全的技术,适用于接受左心室重塑或主动脉根部/瓣膜手术的高危患者,且中期发生二尖瓣狭窄的风险较低。该技术操作简单,其局限性在于可靠识别瓣膜小叶中心。