甘薯摄入量与非酒精性脂肪肝疾病风险之间的纵向关联：TCLSIH 队列研究。
The longitudinal associations between sweet potato intake and the risk of non-alcoholic fatty liver disease: the TCLSIH cohort study.
机构信息
Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, Tianjin, China.
Department of Toxicology and Sanitary Chemistry, School of Public Health, Tianjin Medical University, Tianjin, China.
出版信息
Int J Food Sci Nutr. 2022 Sep;73(6):809-820. doi: 10.1080/09637486.2022.2050997. Epub 2022 Apr 9.
This study aimed to evaluate the longitudinal association between sweet potato intake and risk of NAFLD in the general adult population. In total, the number of 15,787 participants (males, 42.4%) was included in this prospective cohort study. Sweet potato intake was assessed by using a validated food frequency questionnaire. NAFLD was diagnosed by transabdominal sonography during an annual health examination. Cox proportional hazards regression models were fitted to assess the hazard ratios (HRs) and 95% confidence intervals (CIs) across categories of energy-adjusted sweet potato intake. Compared to participants with the lowest tertile of sweet potato intake, the finally adjusted HRs (95% CIs) of incident NAFLD for those with the highest tertile were 0.87 (0.78, 0.97) in males ( for trend = 0.009); and 1.05 (0.92, 1.21) in females ( for trend = 0.52). Our study revealed that sweet potato intake was inversely associated with the risk of NAFLD in males.
本研究旨在评估一般成年人群中甘薯摄入量与非酒精性脂肪性肝病 (NAFLD) 风险之间的纵向关联。在这项前瞻性队列研究中，共纳入了 15787 名参与者（男性占 42.4%）。通过使用经过验证的食物频率问卷评估甘薯摄入量。NAFLD 通过年度健康检查时的腹部超声诊断。使用 Cox 比例风险回归模型评估能量调整后甘薯摄入量各分类的风险比 (HR) 和 95%置信区间 (CI)。与甘薯摄入量最低三分位的参与者相比，最高三分位的男性新发 NAFLD 的最终调整 HR（95%CI）为 0.87（0.78，0.97）（趋势检验=0.009）；女性为 1.05（0.92，1.21）（趋势检验=0.52）。我们的研究表明，男性甘薯摄入量与 NAFLD 风险呈负相关。
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