The University of Memphis, Memphis, TN, USA.
The New School for Social Research, New York, NY, USA.
Addiction. 2022 Nov;117(11):2780-2790. doi: 10.1111/add.15896. Epub 2022 Apr 25.
To estimate the effect of acute alcohol consumption on risk-taking while gambling, examine blood alcohol concentration as a moderator and explore possible moderators of this effect.
DESIGN, SETTING AND PARTICIPANTS: A systematic review and meta-analysis was completed. A Boolean search strategy was used to identify studies that included (a) alcohol consumption as an independent variable; (b) a gambling or risk-taking task; (c) a control or placebo comparison; (d) human participants; and (e) English publications. Descriptive information, sample characteristics and experimental data were extracted from each study. Searched databases included: PsycINFO, Web of Science, Medline, Cochrane Library and ProQuest Dissertations and Theses. Included as participants were experiments that compared the effects of alcohol and non-alcoholic or placebo beverages on risk-taking while gambling.
Comprehensive Meta-Analysis version 3.3.070 was used. Standardized mean differences of risk-taking while gambling between the experimental and control conditions were calculated when studies did not report effect sizes. Random-effects models were used for overall effect and meta-regressions while mixed-effects models were used for subgroup analyses.
Twenty articles containing 47 alcohol versus control comparisons met inclusion criteria. The overall Hedges'g for the difference between groups consuming alcohol and groups consuming a placebo or non-alcoholic drink control was 0.03, 95% confidence interval (CI) = -0.07, 0.12, p = 0.60, indicating no significant difference. Larger effect sizes were found for studies using non-alcoholic control drinks (Hedges' g = 0.30, 95% CI = 0.01, 0.58) compared to placebo beverages (Hedges' g = -0.03, 95% CI = -0.13, 0.06), Cochran's Q = 4.67, p = 0.03.
Finding that acute alcohol consumption had no reliable effect on risk-taking while gambling was consistent with existing animal research. No support was found for the relation between alcohol dose and risk-taking. The significantly larger effect size for experiments using non-alcoholic versus placebo beverages suggests the potential role of expectancy effects.
评估急性饮酒对赌博风险行为的影响,检验血液酒精浓度的调节作用,并探讨该效应的可能调节因素。
设计、地点和参与者:进行了系统评价和荟萃分析。采用布尔搜索策略来确定包括以下内容的研究:(a)酒精消费作为自变量;(b)赌博或风险承担任务;(c)对照或安慰剂比较;(d)人类参与者;和(e)英文出版物。从每项研究中提取描述性信息、样本特征和实验数据。搜索的数据库包括:PsycINFO、Web of Science、Medline、Cochrane Library 和 ProQuest Dissertations and Theses。纳入的参与者包括比较酒精和非酒精或安慰剂饮料对赌博时风险行为影响的实验。
使用 Comprehensive Meta-Analysis version 3.3.070。当研究未报告效应量时,计算实验条件和对照条件下赌博时风险行为的标准化均数差。使用随机效应模型进行总体效应和元回归,使用混合效应模型进行亚组分析。
有 20 篇文章包含 47 项酒精与对照比较符合纳入标准。与饮用安慰剂或非酒精饮料的对照组相比,饮用酒精组的总体 Hedges'g 为 0.03,95%置信区间(CI)为-0.07,0.12,p=0.60,表明无显著差异。使用非酒精对照饮料的研究发现更大的效应量(Hedges'g=0.30,95%CI=0.01,0.58),而安慰剂饮料的效应量较小(Hedges'g=-0.03,95%CI=-0.13,0.06),Cochran's Q=4.67,p=0.03。
发现急性饮酒对赌博时的风险行为没有可靠影响,这与现有的动物研究一致。没有证据支持酒精剂量与风险行为之间的关系。使用非酒精与安慰剂饮料进行的实验中,效应量明显更大,这表明期望效应的潜在作用。