From The Plastic Surgery Foundation; the University of Pittsburgh School of Medicine and Department of Plastic Surgery, University of Pittsburgh; and Department of Surgery, Memorial Sloan Kettering Cancer Center.
Plast Reconstr Surg. 2022 Jun 1;149(6):1118e-1129e. doi: 10.1097/PRS.0000000000009162. Epub 2022 Apr 11.
The American Society of Plastic Surgeons and The Plastic Surgery Foundation launched GRAFT, the General Registry of Autologous Fat Transfer, in October of 2015. This web-accessible registry addresses the need for prospective and systematic data collection, to determine the rates of unfavorable outcomes (complications) of fat grafting. Understanding and avoiding the factors that lead to complications can help establish safe practices for fat grafting.
Data collected between October of 2015 and November of 2019 were summarized for age, sex, indications, processing techniques, and fat graft volume. Rates of complications for fat grafting to various anatomical areas were calculated.
The General Registry of Autologous Fat Transfer collected data on 7052 fat grafting procedures from 247 plastic surgery practices. The mean age of the patients in the registry was 51 years (range, 1 to 89 years), 94 percent were female, and 64 percent of the procedures were for aesthetic indications. Whereas the overall complication rate was low (5.01 percent), the complication rates for fat grafting to the breast and buttocks (7.29 percent and 4.19 percent, respectively) were higher than those for face and other areas (1.94 percent and 2.86 percent, respectively). Oil cysts (2.68 percent) and infections (1.64 percent) were the most common complications of breast fat grafting, whereas seroma (1.84 percent) and palpable mass (1.33 percent) were most common for fat grafting to buttocks. Palpable mass (0.54 percent) and infections (0.54 percent) were most common for fat grafting to face.
The General Registry of Autologous Fat Transfer provides a valuable tool for prospective tracking of fat grafting techniques and complications. Data collected in the registry show low rates of complications for all recipient areas treated with fat grafting.
GRAFT collects real world data on complications of autologous fat grafting procedures. The data collected over 4 years shows low rates of complications for fat grafting. The benchmarking tools available in GRAFT can help enhance techniques and safety of fat grafting.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, III.
美国整形外科学会和整形外科学基金会于 2015 年 10 月推出了 GRAFT，即自体脂肪移植总登记处。这个可通过网络访问的登记处满足了前瞻性和系统性数据收集的需求，以确定脂肪移植不良结局（并发症）的发生率。了解和避免导致并发症的因素有助于为脂肪移植建立安全实践。
总结了 2015 年 10 月至 2019 年 11 月期间的数据，包括年龄、性别、适应证、处理技术和脂肪移植量。计算了不同解剖区域脂肪移植的并发症发生率。
自体脂肪移植总登记处从 247 个整形外科机构收集了 7052 例脂肪移植手术的数据。登记处患者的平均年龄为 51 岁（范围为 1 至 89 岁），94%为女性，64%的手术为美容适应证。尽管总体并发症发生率较低（5.01%），但乳房和臀部脂肪移植的并发症发生率（分别为 7.29%和 4.19%）高于面部和其他部位（分别为 1.94%和 2.86%）。油囊肿（2.68%）和感染（1.64%）是乳房脂肪移植最常见的并发症，而血清肿（1.84%）和可触及肿块（1.33%）是臀部脂肪移植最常见的并发症。可触及肿块（0.54%）和感染（0.54%）是面部脂肪移植最常见的并发症。
自体脂肪移植总登记处为前瞻性跟踪脂肪移植技术和并发症提供了有价值的工具。登记处收集的数据显示，所有接受脂肪移植治疗的部位的并发症发生率均较低。
GRAFT 收集了关于自体脂肪移植手术并发症的真实世界数据。4 年来收集的数据显示，脂肪移植的并发症发生率较低。GRAFT 中提供的基准工具可以帮助提高脂肪移植的技术和安全性。
临床问题/证据水平：风险，III 级。
