建立对 TORC1 信号的空间控制。
Establishing spatial control over TORC1 signaling.
机构信息
Institute of Cell Biology, Biocenter Innsbruck, Medical University of Innsbruck, Innsbruck, Austria.
出版信息
J Cell Biol. 2022 May 2;221(5). doi: 10.1083/jcb.202203136. Epub 2022 Apr 9.
Abstract
Target-of-rapamycin complex 1 resides on lysosomes/vacuoles and additionally on signaling endosomes. Gao et al. (2022. J. Cell Biol.https://doi.org/10.1083/jcb.202109084) set out to define the molecular identity of signaling endosomes, along with players required for the formation and maintenance of this endosomal subpopulation.
摘要
雷帕霉素靶蛋白复合物 1 位于溶酶体/液泡上，也位于信号转导内体上。高等人（2022 年，《细胞生物学杂志》，https://doi.org/10.1083/jcb.202109084）着手定义信号转导内体的分子特征，以及形成和维持该内体亚群所需的参与者。
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