Department of Medicine, Weill Cornell Medicine, 420 E 70th St, Box 331, New York, NY 10021. Email:
Am J Manag Care. 2022 Mar;28(3):108-115. doi: 10.37765/ajmc.2022.88837.
To determine the association of fragmented ambulatory health care with uncontrolled blood pressure (BP) and apparent treatment-resistant hypertension (aTRH) among older adults taking antihypertensive medication, overall and by race and gender.
Cross-sectional study using data from 2868 REasons for Geographic And Racial Differences in Stroke (REGARDS) study participants 66 years and older who completed a study examination in 2013-2016, had Medicare fee-for-service coverage, and were taking antihypertensive medication.
We used logistic regression to analyze the association of fragmented health care with uncontrolled BP and aTRH. Fragmented health care was operationalized as a reversed Bice-Boxerman Index score in the 75th percentile or higher, calculated using the number of ambulatory providers and health care visits in the year preceding the study examination. Uncontrolled BP was defined by systolic BP of at least 140 mm Hg or diastolic BP of at least 90 mm Hg. aTRH was defined by taking 3 or more classes of antihypertensive medication with uncontrolled BP or 4 or more classes with controlled BP.
The overall adjusted odds ratios (95% CIs) for uncontrolled BP, aTRH with controlled BP, and aTRH with uncontrolled BP associated with fragmented health care were 1.10 (0.89-1.37), 1.08 (0.80-1.47), and 1.32 (0.96-1.81), respectively. Fragmented health care was not associated with uncontrolled BP or aTRH among White participants, women, or men. Among Black participants, the odds ratio (95% CI) associated with fragmented health care was 1.21 (0.81-1.82) for uncontrolled BP, 1.22 (0.72-2.07) for aTRH with controlled BP, and 1.82 (1.07-3.11) for aTRH with uncontrolled BP.
Fragmented health care may increase the likelihood of aTRH with uncontrolled BP among older Black adults taking antihypertensive medication.
确定在服用抗高血压药物的老年人中,与不受控制的血压(BP)和明显的治疗抵抗性高血压(aTRH)相关的门诊医疗碎片化,总体上以及按种族和性别进行分析。
使用 2013-2016 年期间完成研究检查且有医疗保险服务付费覆盖并服用抗高血压药物的 2868 名年龄在 66 岁及以上的 REasons for Geographic And Racial Differences in Stroke(REGARDS)研究参与者的数据,进行横断面研究。
我们使用逻辑回归分析了碎片化医疗保健与不受控制的 BP 和 aTRH 的关联。碎片化医疗保健通过在研究检查前一年使用门诊提供者数量和就诊次数计算的逆 Bice-Boxerman 指数得分在第 75 百分位数或更高水平来操作化。不受控制的 BP 定义为收缩压至少 140mmHg 或舒张压至少 90mmHg。aTRH 定义为服用 3 种或更多类抗高血压药物且 BP 不受控制,或服用 4 种或更多类药物且 BP 得到控制。
与碎片化医疗保健相关的总体调整后比值比(95%CI)分别为 1.10(0.89-1.37)、1.08(0.80-1.47)和 1.32(0.96-1.81),用于无控制的 BP、aTRH 控制的 BP 和 aTRH 无控制的 BP。在白人参与者、女性或男性中,碎片化医疗保健与无控制的 BP 或 aTRH 无关。在黑人参与者中,与碎片化医疗保健相关的比值比(95%CI)分别为 1.21(0.81-1.82)用于无控制的 BP、1.22(0.72-2.07)用于控制的 BP 和 1.82(1.07-3.11)用于无控制的 BP。
在服用抗高血压药物的老年黑人中,碎片化医疗保健可能会增加伴有不受控制的 BP 的 aTRH 的可能性。