Gastroenterology Department, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Mexico City, Mexico.
Gac Med Mex. 2022;158(1):41-47. doi: 10.24875/GMM.M22000639.
Dietary fiber intake helps in the remission of ulcerative colitis (UC).
To evaluate if there is an association between the amount of fiber in usual diet and disease activity in patients with UC.
Cross-sectional study of a cohort of patients with UC. Dietary fiber intake was calculated and compared with the recommended amount (14 g/1000 kcal) with Mann-Whitney's U-test. Using Spearman's correlation coefficient, the number of relapses and the amount of consumed fiber were analyzed, and the relationship of dietary fiber consumption with disease activity was established by logistic regression.
The group without ongoing UC activity consumed a higher amount of dietary fiber (20 g, IQR = 18-26, p = 0.062), and 47% consumed more than the recommended amount; the logistic regression analysis showed that compliance with recommended fiber consumption was associated as a protective factor against UC current activity (OR = 0.227, p = 0.032). As for dietary fiber intake and the number of relapses within previous year, an inversely proportional correlation was observed (r = -0.399, p = 0.011).
Consumption of the recommended dietary fiber amount in the general population had a protective effect against UC activity in Mexican patients.
膳食纤维的摄入有助于溃疡性结肠炎（UC）的缓解。
评估溃疡性结肠炎患者日常饮食中纤维含量与疾病活动度之间是否存在关联。
对溃疡性结肠炎患者队列进行横断面研究。计算膳食纤维摄入量，并与推荐量（14 g/1000 kcal）进行比较，采用曼-惠特尼 U 检验。采用 Spearman 相关系数分析复发次数与消耗纤维量之间的关系，并通过逻辑回归分析膳食纤维摄入与疾病活动度的关系。
无 UC 活动的组消耗了更高量的膳食纤维（20 g，IQR = 18-26，p = 0.062），47%的人消耗超过了推荐量；逻辑回归分析显示，推荐纤维摄入量的依从性与 UC 目前的活动呈保护因素相关（OR = 0.227，p = 0.032）。至于膳食纤维的摄入与前一年的复发次数，观察到呈反比关系（r = -0.399，p = 0.011）。
墨西哥患者普遍摄入推荐量的膳食纤维对 UC 活动具有保护作用。
