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饮食、氧化应激与不同类型青光眼患者血清营养素水平:系统评价

Diet, Oxidative Stress, and Blood Serum Nutrients in Various Types of Glaucoma: A Systematic Review.

机构信息

Department of Ophthalmology, Medical University of Białystok, M. Skłodowskiej-Curie 24a, 15-276 Białystok, Poland.

Department of Bromatology, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Białystok, Mickiewicza 2D, 15-222 Białystok, Poland.

出版信息

Nutrients. 2022 Mar 29;14(7):1421. doi: 10.3390/nu14071421.

DOI:10.3390/nu14071421
PMID:35406033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9002851/
Abstract

Glaucoma is one of the most common causes of irreversible vision loss worldwide. It is an insidious disease with a multifactorial pathogenesis. Despite progress in treatment methods, prevention and lifestyle modifications may be useful in slowing the progression of this disease. This systematic review aimed to evaluate the influence of diet, oxidative stress, and disturbances in blood serum levels of nutrients on the incidence and severity of glaucoma based on scientific reports on the role of nutrition in the pathogenesis and course of glaucoma. This paper presents an analysis of the above issues; however, further research is required to develop this topic. Future clinical trials are needed to assess the influence of nutrition and to develop nutritional management strategies for patients with glaucoma.

摘要

青光眼是全球最常见的导致不可逆视力丧失的原因之一。它是一种具有多种发病因素的隐匿性疾病。尽管在治疗方法上取得了进展,但预防和生活方式的改变可能有助于减缓这种疾病的进展。本系统评价旨在根据有关营养在青光眼发病机制和病程中的作用的科学报告,评估饮食、氧化应激以及血清营养素水平紊乱对青光眼发病率和严重程度的影响。本文对上述问题进行了分析,但需要进一步研究来深入探讨这个话题。需要开展未来的临床试验来评估营养的影响,并为青光眼患者制定营养管理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2e/9002851/0074100122a5/nutrients-14-01421-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2e/9002851/0074100122a5/nutrients-14-01421-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2e/9002851/0074100122a5/nutrients-14-01421-g001.jpg

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Healthy Lifestyle Score and Incidence of Glaucoma: The Sun Project.健康生活方式评分与青光眼发病率:太阳项目。
Nutrients. 2022 Feb 12;14(4):779. doi: 10.3390/nu14040779.
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Association of serum retinol concentration with normal-tension glaucoma.血清视黄醇浓度与正常眼压性青光眼的关系。
Deliberate dietary adjustments may not mitigate the progression of glaucoma: A two-sample Mendelian randomization study.
刻意的饮食调整可能无法减缓青光眼的进展:一项两样本孟德尔随机化研究。
Medicine (Baltimore). 2025 Jul 18;104(29):e42944. doi: 10.1097/MD.0000000000042944.
4
CD38-NAD(+) Axis: New Insights into Glaucoma Therapy.CD38 - NAD(+)轴:青光眼治疗的新见解
Mol Neurobiol. 2025 Jul 22. doi: 10.1007/s12035-025-05243-3.
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