Du Chunbao, Du Ting, Zhou Joey Tianyi, Zhu Yanan, Jia Xingang, Cheng Yuan
College of Chemistry and Chemical Engineering, Xi'an Shiyou University, Xi'an 710065, China.
Institute of High Performance Computing, A*STAR, Singapore 138632, Singapore.
Nanomaterials (Basel). 2022 Apr 1;12(7):1181. doi: 10.3390/nano12071181.
Graphene-based nanocomposite films (NCFs) are in high demand due to their superior photoelectric and thermal properties, but their stability and mechanical properties form a bottleneck. Herein, a facile approach was used to prepare nacre-mimetic NCFs through the non-covalent self-assembly of graphene oxide (GO) and biocompatible proteins. Various characterization techniques were employed to characterize the as-prepared NCFs and to track the interactions between GO and proteins. The conformational changes of various proteins induced by GO determined the film-forming ability of NCFs, and the binding of bull serum albumin (BSA)/hemoglobin (HB) on GO's surface was beneficial for improving the stability of as-prepared NCFs. Compared with the GO film without any additive, the indentation hardness and equivalent elastic modulus could be improved by 50.0% and 68.6% for GO-BSA NCF; and 100% and 87.5% for GO-HB NCF. Our strategy should be facile and effective for fabricating well-designed bio-nanocomposites for universal functional applications.
基于石墨烯的纳米复合薄膜（NCFs）因其优异的光电和热性能而有很高的需求，但其稳定性和机械性能却成为了瓶颈。在此，我们采用一种简便的方法，通过氧化石墨烯（GO）与生物相容性蛋白质的非共价自组装来制备仿珍珠层的NCFs。采用了各种表征技术来表征所制备的NCFs，并追踪GO与蛋白质之间的相互作用。GO诱导的各种蛋白质的构象变化决定了NCFs的成膜能力，牛血清白蛋白（BSA）/血红蛋白（HB）在GO表面的结合有利于提高所制备的NCFs的稳定性。与没有任何添加剂的GO薄膜相比，GO-BSA NCF的压痕硬度和等效弹性模量可分别提高50.0%和68.6%；GO-HB NCF则可分别提高100%和87.5%。我们的策略对于制造用于通用功能应用的精心设计的生物纳米复合材料应该是简便且有效的。
