Cheng Ya-Fu, Cheng Ching-Yuan, Huang Chang-Lun, Hung Wei-Heng, Wang Bing-Yen
Division of Thoracic Surgery, Department of Surgery, Changhua Christian Hospital, Changhua 500, Taiwan.
School of Medicine, Chung Shan Medical University, Taichung 201, Taiwan.
J Clin Med. 2022 Mar 28;11(7):1882. doi: 10.3390/jcm11071882.
Empyema is known as a serious infection, and outcomes of empyema cases remain poor. Pleural fluid culture and blood culture have been reported to give unsatisfactory results. We introduce a novel pleural peels tissue culture during surgery and aim to improve the culture results of empyema.
This was a retrospective study and was obtained from our institute. Patients with stage II or III empyema undergoing video-assisted thoracic surgery decortication from January 2019 to June 2021 were included in the study.
There were 239 patients that received a pleural peels tissue culture, a pleural fluid culture, and a blood culture concurrently during the perioperative period. Of these, 153 patients had at least one positive culture and 86 patients showed triple negative culture results. The positive culture rates were 46.9% for pleural peels tissue cultures, 46.0% for pleural fluid cultures, and 10% for blood cultures. The combination of pleural peels tissue culture and pleural fluid culture increased the positive rate to 62.7%. Streptococcus species and Staphylococcus species were the most common pathogens.
The combination of pleural peels tissue culture and pleural fluid culture is an effective method to improve the positive culture rate in empyema.
脓胸是一种严重的感染，脓胸病例的治疗效果仍然较差。据报道，胸腔积液培养和血培养的结果并不理想。我们在手术过程中引入了一种新型的胸膜剥脱组织培养方法，旨在提高脓胸的培养结果。
这是一项回顾性研究，数据来自我们的研究所。纳入2019年1月至2021年6月期间接受电视辅助胸腔镜手术剥脱术的II期或III期脓胸患者。
239例患者在围手术期同时接受了胸膜剥脱组织培养、胸腔积液培养和血培养。其中，153例患者至少有一次培养结果为阳性，86例患者的培养结果为三项均阴性。胸膜剥脱组织培养的阳性培养率为46.9%，胸腔积液培养为46.0%，血培养为10%。胸膜剥脱组织培养和胸腔积液培养相结合可使阳性率提高到62.7%。链球菌属和葡萄球菌属是最常见的病原体。
胸膜剥脱组织培养和胸腔积液培养相结合是提高脓胸培养阳性率的有效方法。
