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老年患者心力衰竭住院后,比较老年科医生和心脏病专家多学科干预与常规护理的随机对照试验:SENECOR研究。

Randomized Controlled Trial Comparing a Multidisciplinary Intervention by a Geriatrician and a Cardiologist to Usual Care after a Heart Failure Hospitalization in Older Patients: The SENECOR Study.

作者信息

Herrero-Torrus Marta, Badosa Neus, Roqueta Cristina, Ruiz-Bustillo Sonia, Solé-González Eduard, Belarte-Tornero Laia C, Valdivielso-Moré Sandra, Vázquez Olga, Farré Núria

机构信息

Geriatrics Department, Hospital del Mar, 08003 Barcelona, Spain.

Heart Failure Unit, Cardiology Department, Hospital del Mar, 08003 Barcelona, Spain.

出版信息

J Clin Med. 2022 Mar 30;11(7):1932. doi: 10.3390/jcm11071932.

Abstract

BACKGROUND

The prognosis of older patients after a heart failure (HF) hospitalization is poor.

METHODS

In this randomized trial, we consecutively assigned 150 patients 75 years old or older with a recent heart failure hospitalization to follow-up by a cardiologist (control) or follow-up by a cardiologist and a geriatrician (intervention). The primary outcome was all-cause hospitalization at a one-year follow-up.

RESULTS

All-cause hospitalization occurred in 47 of 75 patients (62.7%) in the intervention group and in 58 of 75 patients (77.3%) in the control group (hazard ratio, 0.67; 95% confidence interval, 0.46 to 0.99; = 0.046). The number of patients with at least one HF hospitalization was similar in both groups (34.7% in the intervention group vs. 40% in the control group, = 0.5). There were a total of 236 hospitalizations during the study period. The main reasons for hospitalization were heart failure (38.1%) and infection (14.8%). Mortality was 24.7%. Heart failure was the leading cause of mortality (54.1% of all deaths), without differences between groups.

CONCLUSIONS

A follow-up by a cardiologist and geriatrician in older patients after an HF hospitalization was superior to a cardiologist's follow-up in reducing all-cause hospitalization in older patients. (Funded by Beca Primitivo de la Vega, Fundación MAPFRE.

CLINICALTRIALS

gov number, NCT03555318).

摘要

背景

老年患者心力衰竭(HF)住院后的预后较差。

方法

在这项随机试验中,我们将150名75岁及以上近期有心力衰竭住院史的患者连续分配至由心脏病专家进行随访(对照组)或由心脏病专家和老年病专家进行随访(干预组)。主要结局是1年随访时的全因住院情况。

结果

干预组75例患者中有47例(62.7%)发生全因住院,对照组75例患者中有58例(77.3%)发生全因住院(风险比,0.67;95%置信区间,0.46至0.99;P = 0.046)。两组中至少有一次心力衰竭住院的患者数量相似(干预组为34.7%,对照组为40%,P = 0.5)。研究期间共有236次住院。住院的主要原因是心力衰竭(38.1%)和感染(14.8%)。死亡率为24.7%。心力衰竭是主要死因(占所有死亡的54.1%),两组之间无差异。

结论

心力衰竭住院后的老年患者由心脏病专家和老年病专家进行随访在降低老年患者全因住院方面优于仅由心脏病专家进行随访。(由贝卡·普里米蒂沃·德拉维加资助,MAPFRE基金会。临床试验注册号,NCT03555318)

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb09/8999953/be9b30260f38/jcm-11-01932-g001.jpg

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