Cruz Nuno, Tondela João Paulo, Martins Maria Inês, Velasco-Ortega Eugenio, Gil Javier
School of Dentistry, Universitat Internacional de Catalunya (UIC), C. Josep Trueta s/n, 08195 Sant Cugat del Vallès, Spain.
Bioengineering Institute of Technology, International University of Catalonia, Josep Trueta s/n, 08195 Barcelona, Spain.
Materials (Basel). 2022 Apr 4;15(7):2651. doi: 10.3390/ma15072651.
Titanium dental meshes have a wide application in order to ensure the retention of calcium phosphate-based biomaterials to regenerate bone tissue. These meshes are temporary and must grow a soft tissue to prevent bacterial colonization and provide stability. In this work, we aimed to optimize the roughness of the meshes to obtain a good biological seal while maintaining a behavior that did not favor bacterial colonization. To this end, six types of surfaces were studied: machined as a control, polished, sandblasted with three different alumina sizes and sintered. The roughness, contact angles and biological behavior of the samples using fibroblast cultures at 7, 24 and 72 h were determined as well as cytotoxicity studies. Cultures of two very common bacterial strains in the oral cavity were also carried out: and . The results showed that the samples treated with alumina particles by sandblasting at 200 micrometers were the ones that performed best with fibroblasts and also with the number of bacterial colonies in both strains. According to the results, we see in this treatment a candidate for the surface treatment of dental meshes with an excellent performance.
钛牙科网在确保基于磷酸钙的生物材料保留以再生骨组织方面有广泛应用。这些网是临时性的，必须生长出软组织以防止细菌定植并提供稳定性。在这项工作中，我们旨在优化网的粗糙度，以获得良好的生物密封，同时保持不利于细菌定植的特性。为此，研究了六种类型的表面：作为对照的机械加工表面、抛光表面、用三种不同粒度的氧化铝喷砂处理的表面以及烧结表面。测定了使用成纤维细胞培养7小时、24小时和72小时的样品的粗糙度、接触角和生物学行为以及细胞毒性研究。还进行了口腔中两种非常常见的细菌菌株的培养： 和 。结果表明，用200微米氧化铝颗粒喷砂处理的样品在成纤维细胞以及两种菌株的细菌菌落数量方面表现最佳。根据结果，我们认为这种处理是牙科网表面处理的一个性能优异的候选方法。
