Psychiatric Clinic, Department of Clinical and Experimental Medicine, University of Pisa, Via Roma 67, 56100 Pisa, Italy.
Occupational Health Department, Azienda Ospedaliero Universitaria Pisana, Via Paradisa 2, 56124 Pisa, Italy.
Int J Environ Res Public Health. 2022 Mar 23;19(7):3809. doi: 10.3390/ijerph19073809.
The adult autism subthreshold spectrum model appears to be a useful tool for detecting possible vulnerability factors in order to develop mental disorders in the contest of work-related stress. The aim of the present study is to analyze the relationship between autism, mood, and post-traumatic spectrum in a cohort of subjects complaining of work-related stress before the COVID-19 pandemic. The authors carried out a retrospective investigation of both medical records and self-assessment tools of a sample of subjects evaluated at the Occupational Health Department of a University hospital in central Italy. Data showed significant correlations between the AdAS spectrum, TALS-SR, and MOODS total and domain scores. A multiple linear regression evidenced that both the AdAS spectrum and TAL-SR significantly predict the MOODS scores. In particular, mediation analysis showed both a direct and indirect, mediated by TALS-SR, effect of the AdAS Spectrum on the MOODS-SR. These results corroborate the role of autistic traits in influencing the traumatic impact of work-related stress and the development of mood spectrum symptoms.
成人自闭症亚阈值谱模型似乎是一种有用的工具，可以检测可能的脆弱性因素，以便在与工作相关的压力背景下发展精神障碍。本研究旨在分析自闭症、情绪和创伤后谱在一组主诉与 COVID-19 大流行前工作相关压力的受试者中的关系。作者对意大利中部一所大学医院职业健康部门评估的受试者的病历和自我评估工具进行了回顾性调查。研究结果显示，AdAS 谱、TALS-SR 和 MOODS 总分和域评分之间存在显著相关性。多元线性回归表明，AdAS 谱和 TAL-SR 均能显著预测 MOODS 评分。具体而言，中介分析表明，AdAS 谱对 MOODS-SR 的影响既有直接影响，也有通过 TALS-SR 的间接影响。这些结果证实了自闭症特征在影响与工作相关压力相关的创伤影响和情绪谱症状发展方面的作用。
