Dell'Osso Liliana, Nardi Benedetta, Bonelli Chiara, Gravina Davide, Benedetti Francesca, Amatori Giulia, Battaglini Simone, Massimetti Gabriele, Luciano Mario, Berardelli Isabella, Brondino Natascia, De Gregorio Marianna, Deste Giacomo, Nola Marta, Reitano Antonino, Muscatello Maria Rosaria Anna, Pompili Maurizio, Politi Pierluigi, Vita Antonio, Carmassi Claudia, Cremone Ivan Mirko, Carpita Barbara, Maj Mario
Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Department of Psychiatry, University of Campania "Luigi Vanvitelli", Naples, Italy.
Front Psychiatry. 2023 May 18;14:1124241. doi: 10.3389/fpsyt.2023.1124241. eCollection 2023.
Recent literature has highlighted that catatonia may be more prevalent among psychiatric patients than previously thought, beginning from autism spectrum disorders (ASD), for which it has been suggested to represent a severe late consequence, but also among individuals with mood disorders and borderline personality disorder (BPD). Interestingly, one critical point shared by these conditions is the increased risk of suicidality. The aim of this study was to evaluate how the presence and the prevalence of catatonic symptoms may shape and correlate with suicidal risk in a sample of individuals with major depressive disorder (MDD) or BPD.
We recruited two clinical samples of subjects (BPD and MDD) and a control group without a diagnosis according to DSM-5 (CTL). Subjects were assessed with the catatonia spectrum (CS) and the MOODS-SR for evaluating suicidality.
In the total sample, suicidality score was significantly and positively correlated with all CS domains and CS total score. Correlation and regression analyses highlighted specific patterns of association among Catatonia spectrum domains and suicidality in the MDD and BPD group and in the total sample.
In both disorders, higher catatonic traits are linked to higher suicidal tendencies, confirming the high risk of suicide for this population. However, different patterns of association between catatonic symptoms and suicidality were highlighted in the two disorders.
近期文献强调，紧张症在精神科患者中可能比之前认为的更为普遍，从自闭症谱系障碍（ASD）患者群体开始，紧张症被认为是ASD严重的晚期后果，而且在心境障碍和边缘型人格障碍（BPD）患者中也较为普遍。有趣的是，这些病症共有的一个关键点是自杀风险增加。本研究的目的是评估在重度抑郁症（MDD）或BPD患者样本中，紧张症症状的存在和患病率如何影响自杀风险并与之相关。
我们招募了两组临床样本对象（BPD组和MDD组）以及一个未根据《精神疾病诊断与统计手册》第5版（DSM-5）进行诊断的对照组（CTL组）。使用紧张症谱系量表（CS）和MOODS-SR量表对对象进行评估，以评估自杀倾向。
在总样本中，自杀倾向得分与所有CS领域得分及CS总分均呈显著正相关。相关性和回归分析突出了MDD组、BPD组以及总样本中紧张症谱系领域与自杀倾向之间的特定关联模式。
在这两种病症中，较高的紧张症特质与较高的自杀倾向相关，证实了该人群的高自杀风险。然而，两种病症中紧张症症状与自杀倾向之间的关联模式有所不同。
