Trindade Paula Gasparini Emery, Santos Raquel Luiza, Johannessen Aud, Neto Jose Pedro Simões, Dourado Marcia Cristina Nascimento
Center for Alzheimer's Disease, Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Brazil.
Norwegian Advisory Unit for Aging and Health Vestfold Health Trust, Tønsberg, Norway.
J Alzheimers Dis Rep. 2020 Oct 8;4(1):405-415. doi: 10.3233/ADR-200227.
Awareness of functional status may underlie specific profiles and differences related to stage severity in individuals with Alzheimer's disease (AD).
This study aimed to assess self-reported experiences of awareness of functional activity in people with mild and moderate AD.
This is a mixed methods approach. The qualitative part was conducted through semi-structured interviews concerning the experiences and awareness of deficits in 38 older adults with mild or moderate AD. The quantitative approach included a comparison between groups with regard to concerns of awareness and clinic and demographic data.
Impairment on awareness of disease and awareness of functional deficits was observed even in the mild stages of AD. There was also a noticeable progression of impairments of both kinds of awareness from mild to moderate stage of disease. The majority of participants with mild and moderate AD were partially aware of their functional deficits. Both groups of participants reported some negative impact; however, they were not able to entirely describe their functional status. Also, deficits to recognize the need for help with hygiene and general tasks were observed. Significant differences were found in awareness of need for help with general tasks and awareness of need for help with hygiene tasks.
People with mild and moderate AD may describe their aware of the disease better than specific functional deficits, and most of them can provide some reports concerning to the impact of the disease.
对功能状态的认知可能是阿尔茨海默病（AD）患者特定特征及与疾病严重程度相关差异的基础。
本研究旨在评估轻度和中度AD患者自我报告的功能活动认知体验。
这是一种混合方法。定性部分通过对38名轻度或中度AD老年患者进行关于缺陷体验和认知的半结构化访谈来开展。定量方法包括在认知关注、临床及人口统计学数据方面对组间进行比较。
即使在AD的轻度阶段，也观察到疾病认知和功能缺陷认知受损。从疾病的轻度到中度阶段，这两种认知的损害也有明显进展。大多数轻度和中度AD参与者部分意识到自己的功能缺陷。两组参与者均报告了一些负面影响；然而，他们无法完全描述自己的功能状态。此外，还观察到在认识到卫生和一般任务需要帮助方面存在缺陷。在一般任务需要帮助的认知和卫生任务需要帮助的认知方面发现了显著差异。
轻度和中度AD患者对疾病的认知可能比对特定功能缺陷的认知更好，并且他们中的大多数人可以提供一些关于疾病影响的报告。
