Pharmacy Department, Dijon Bourgogne University Hospital, EPICAD LNC UMR 1231, 21000 Dijon, France.
Biological Haematology Department, Dijon Bourgogne University Hospital, Haematological Malignancies Registry, LNC UMR 1231, 21000 Dijon, France.
Int J Environ Res Public Health. 2022 Mar 26;19(7):3957. doi: 10.3390/ijerph19073957.
Background: We aimed to investigate the impact of the first COVID-19 lockdown on medication adherence, physician access, lifestyle behaviours, and mental health in patients with chronic conditions. Methods: A cross-sectional phone survey was conducted in 1274 housebound adults recruited from 8 regional chronic disease cohorts (CLEO CD study: NCT04390126). Results: Medication adherence was 97%; 305 (41%) patients declared that at least one scheduled visit with a physician was missed during the first lockdown. The main changes in lifestyle behaviours were deterioration in sleep time (duration and/or quality; 71%), increase in screen time (46%), and decrease in physical activity (46%). Nineteen percent experienced psychological distress (Kessler-6 score ≥ 5). An urban living place (OR, 1.76 vs. rural; 95% CI, 1.32−2.33; p = 10−4), worse self-reported mental health (OR, 1.62 vs. about the same or better; 95% CI, 1.17−2.25; p = 0.003), and a K6 score ≥ 5 (OR, 1.52 vs. <5; 95% CI, 1.05−2.21; p = 0.03) were independent factors associated with at least one unhealthy behaviour. Conclusions: Encouraging results were observed in terms of medication adherence. Caution is needed in chronic disease patients living in urban places as well as those presenting psychological distress and worse self-reported mental health to reduce unhealthy behaviours.
本研究旨在调查首次 COVID-19 封锁对慢性病患者的药物依从性、医生就诊、生活方式行为和心理健康的影响。
我们对来自 8 个区域性慢性病队列的 1274 名居家成年人（CLEO CD 研究：NCT04390126）进行了横断面电话调查。
药物依从性为 97%；305 名（41%）患者表示，在首次封锁期间至少错过了一次预约就诊。生活方式行为的主要变化是睡眠时间（持续时间和/或质量；71%）恶化、屏幕时间增加（46%）和体力活动减少（46%）。19%的患者出现心理困扰（Kessler-6 评分≥5）。与农村相比，城市居住地点（OR，1.76；95%CI，1.32−2.33；p=10−4）、自我报告的心理健康状况较差（OR，1.62；95%CI，1.17−2.25；p=0.003）和 K6 评分≥5（OR，1.52；95%CI，1.05−2.21；p=0.03）是与至少一种不健康行为相关的独立因素。
在药物依从性方面观察到了令人鼓舞的结果。对于居住在城市地区、存在心理困扰和自我报告心理健康状况较差的慢性病患者，需要谨慎对待，以减少不健康行为。
