Pharmacy Department, University Hospital, Dijon, France; LNC UMR 1231, University Hospital, Dijon, France.
PEC2, EA 7460 Dijon, France.
Int J Cardiol. 2021 Jan 15;323:285-287. doi: 10.1016/j.ijcard.2020.08.094. Epub 2020 Sep 1.
We aimed to evaluate the impact of coronavirus disease 2019 (COVID-19)-related lockdown on adherence to lifestyle and drug regimens in stay-at-home chronic coronary syndromes patients living in urban and rural areas.
A cross-sectional population-based study was perfomed in patients with chronic coronary syndromes. A sample of 205 patients was randomly drawn from the RICO (Observatoire des infarctus de Côte d'Or) cohort. Eight trained interviewers collected data by phone interview during week 16 (April 13 to April 19), i.e. 4 weeks after implementation of the French lockdown (start March 17, 2020).
Among the 195 patients interviewed (of the 205, 3 had died, 1 declined, 6 lost), mean age was 65.5 ± 11.1 years. Only six patients (3%) reported drug discontinuation, mainly driven by media influence or family members. All 166 (85%) patients taking aspirin continued their prescribed daily intake. Lifestyle rules were less respected since almost half (45%) declared >25% reduction in physical activity, 26% of smokers increased their tobacco consumption by >25%, and 24% of patients increased their body weight > 2 kg. The decrease in physical activity and the increase in smoking were significantly greater in urban patients (P < .05).
The COVID-19-related lockdown had a negative impact on lifestyle in a representative sample of stay-at-home CCS patients.
我们旨在评估与 2019 年冠状病毒病（COVID-19）相关的封锁对居住在城乡的居家慢性冠状动脉综合征患者坚持生活方式和药物治疗方案的影响。
这是一项在慢性冠状动脉综合征患者中进行的基于人群的横断面研究。从 RICO（科多尔省心肌梗死观察站）队列中随机抽取了 205 例患者作为样本。8 名经过培训的访谈员通过电话访谈在第 16 周（4 月 13 日至 4 月 19 日）收集数据，即法国封锁开始后第 4 周（2020 年 3 月 17 日开始）。
在接受访谈的 195 例患者中（205 例中有 3 例死亡，1 例拒绝，6 例失联），平均年龄为 65.5±11.1 岁。仅有 6 例患者（3%）报告停止用药，主要是受媒体影响或家庭成员影响。所有 166 例（85%）服用阿司匹林的患者继续按规定每日服用。生活方式规则的遵守情况较差，因为近一半（45%）患者报告体力活动减少>25%，26%的吸烟者增加了>25%的烟草消费，24%的患者体重增加了>2 公斤。城市患者的体力活动减少和吸烟增加更为明显（P<.05）。
在居家慢性冠状动脉综合征患者的代表性样本中，COVID-19 相关的封锁对生活方式产生了负面影响。
