Jezierska Karolina, Sękowska-Namiotko Anna, Pala Bartłomiej, Lietz-Kijak Danuta, Gronwald Helena, Podraza Wojciech
Department of Medical Physics, Pomeranian Medical University, 71-073 Szczecin, Poland.
Department of Propaedeutic, Physical Diagnostics and Dental Physiotherapy, Pomeranian Medical University, 70-204 Szczecin, Poland.
Int J Environ Res Public Health. 2022 Mar 28;19(7):4012. doi: 10.3390/ijerph19074012.
There is an ongoing debate on the benefits of magnetic stimulation in neurological disorders.
We aimed to evaluate the influence of magnetic stimulation on blood oxygenation of the motor cortex using functional near-infrared spectroscopy (fNIRS).
A total of 16 healthy volunteer participants were subjected to four protocols. In the first two protocols, the participants remained at rest without (and then with) magnetic stimulation. In the next two protocols, motor cortex stimulation was achieved using a finger-tapping task, with and without magnetic stimulation. Changes in blood oxygenation levels within the motor cortex were recorded and analysed.
No characteristic changes in the blood oxygenation level-dependent responses were observed in resting participants after magnetic stimulation. No statistically significant difference was observed in the amplitude of the fNIRS signal before and after magnetic stimulation. We observed characteristic blood oxygenation level-dependent responses after the finger-tapping task in the second protocol, but not after magnetic stimulation.
Although we did not observe any measurable effect of the magnetic field on the haemodynamic response of the motor cortex, understanding the mechanism(s) of magnetic stimulation may be important. Additional, detailed studies are needed to prove or negate the potential of this medical procedure.
关于磁刺激在神经疾病中的益处存在持续的争论。
我们旨在使用功能近红外光谱技术（fNIRS）评估磁刺激对运动皮层血液氧合的影响。
总共16名健康志愿者参与了四个实验方案。在前两个方案中，参与者在无（然后有）磁刺激的情况下保持休息状态。在接下来的两个方案中，通过手指敲击任务实现对运动皮层的刺激，分别有无磁刺激。记录并分析运动皮层内血液氧合水平的变化。
磁刺激后，休息的参与者未观察到血液氧合水平依赖性反应的特征性变化。磁刺激前后fNIRS信号的幅度未观察到统计学上的显著差异。在第二个方案的手指敲击任务后，我们观察到了特征性的血液氧合水平依赖性反应，但磁刺激后未观察到。
尽管我们未观察到磁场对运动皮层血流动力学反应有任何可测量的影响，但了解磁刺激的机制可能很重要。需要进行更多详细研究来证明或否定这种医疗程序的潜力。
