1st Department of Psychiatry, Eginition Hospital, Medical School, National & Kapodistrian University of Athens, 11528 Athens, Greece.
1st Department of Dermatology-Venereology, Andreas Sygros Hospital, Medical School, National & Kapodistrian University of Athens, 16121 Athens, Greece.
Int J Environ Res Public Health. 2022 Mar 29;19(7):4029. doi: 10.3390/ijerph19074029.
Psoriasis is a chronic, relapsing, inflammatory disease with a high risk of developing mental health difficulties.
The purposes of the study were to evaluate in moderate-to-severe psoriasis (a) the prevalence of depression and psychopathology, (b) the relationship between depression, psychopathology symptoms, and alexithymia, including its three dimensions, difficulty in identifying feelings (DIF), difficulty in describing feelings (DDF), and externally oriented thinking (EOT), and (c) to establish a novel index for the development of depression according to patients' psychopathological profile.
In 104 patients, alexithymia was evaluated with the Toronto Alexithymia Scale (TAS-20), depression with the Beck Depression Inventory (BDI), and psychopathology with the Brief Symptom Inventory SCL-90 (SCL90). A psychopathology index that combines information from the BDI and SCL90 scales was constructed and the performance of the index with alexithymia was examined.
Female patients and active smokers score higher on BDI and SCL90 scales. Overweight patients tend to score arithmetically higher. The psychopathology index developed correlates significantly with age, DIF, DDF, and TAS-20. DIF, DDF, and TAS-20 are significant predictors of the psychopathology index. Patients with alexithymia/possible alexithymia are six times as likely to score higher in one of the psychopathology scales.
Alexithymia is a significant factor in the development of psychopathology in psoriasis patients. The use of the proposed novel psychopathology index could be essential in order to identify patients with moderate-to-severe psoriasis who are more likely to experience depression and psychopathology. This could have an impact on the decision-making of psoriasis treatment and monitoring of the patient.
银屑病是一种慢性、复发性、炎症性疾病，心理健康问题的风险较高。
本研究旨在评估中重度银屑病患者：(a) 抑郁和精神病理学的患病率；(b) 抑郁、精神病理学症状与述情障碍之间的关系，包括述情障碍的三个维度：即难以识别自身感受（DIF）、难以描述感受（DDF）和外向思维（EOT）；(c) 根据患者的精神病理特征，建立一种新的抑郁发展指标。
对 104 例患者进行了多伦多述情障碍量表（TAS-20）、贝克抑郁量表（BDI）和简明症状量表 SCL-90（SCL90）的评估。构建了一种结合 BDI 和 SCL90 量表信息的精神病理学指数，并检查了该指数与述情障碍的相关性。
女性患者和主动吸烟者在 BDI 和 SCL90 量表上的评分较高。超重患者的评分往往更高。所开发的精神病理学指数与年龄、DIF、DDF 和 TAS-20 显著相关。DIF、DDF 和 TAS-20 是精神病理学指数的显著预测因子。有述情障碍/可能述情障碍的患者在其中一种精神病理学量表上的评分升高的可能性是其他人的六倍。
述情障碍是银屑病患者精神病理学发展的重要因素。使用所提出的新型精神病理学指数对于识别更有可能出现抑郁和精神病理学的中重度银屑病患者可能至关重要。这可能会影响银屑病治疗的决策和患者的监测。
