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银屑病患者的自杀风险与精神疾病共病情况

Suicide risk and psychiatric comorbidity in patients with psoriasis.

作者信息

Pompili Maurizio, Innamorati Marco, Trovarelli Sara, Narcisi Alessandra, Bellini Samantha, Orsini Diego, Forte Alberto, Erbuto Denise, Botti Elisabetta, Lamis Dorian A, Girardi Paolo, Costanzo Antonio

机构信息

Department of Neurosciences, Mental Health and Sensory Organs, Suicide Prevention Centre, S.Andrea Hospital, University of Rome "La Sapienza", Rome, Italy.

Department of Human Sciences, European University of Rome, Rome, Italy.

出版信息

J Int Med Res. 2016 Sep;44(1 suppl):61-66. doi: 10.1177/0300060515593253.

DOI:10.1177/0300060515593253
PMID:27683142
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5536523/
Abstract

OBJECTIVES

To examine the occurrence of stressful life events, psychological comorbidity and suicide risk in patients with psoriasis or other dermatological conditions.

METHODS

Consecutive adult outpatients with psoriasis or other dermatological conditions completed a sociodemographic questionnaire and the Hamilton scales for depression and anxiety.

RESULTS

The study included 157 patients (91 with psoriasis; 66 with other conditions [melanoma; allergy]). Patients with psoriasis were significantly more likely to have experienced major life events in the 12 months before diagnosis, have had a psychiatric diagnosis and to have experienced past suicidal ideation than patients with other dermatological conditions.

CONCLUSIONS

Patients with psoriasis have an increased risk of psychiatric comorbidities, suicidal ideation, and long-term course of the disease compared with patients who have other dermatological conditions. Psychiatric assessment is highly recommended in patients with psoriasis.

摘要

目的

研究银屑病或其他皮肤病患者中应激性生活事件、心理共病及自杀风险的发生情况。

方法

连续纳入患有银屑病或其他皮肤病的成年门诊患者,他们完成了一份社会人口统计学调查问卷以及汉密尔顿抑郁和焦虑量表。

结果

该研究纳入了157例患者(91例银屑病患者;66例患有其他疾病[黑色素瘤;过敏])。与其他皮肤病患者相比,银屑病患者在诊断前12个月内经历重大生活事件、有精神科诊断以及有过自杀意念的可能性显著更高。

结论

与其他皮肤病患者相比,银屑病患者发生精神共病、自杀意念及疾病长期病程的风险增加。强烈建议对银屑病患者进行精神科评估。

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本文引用的文献

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The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis.抗菌肽 LL37 是银屑病中的 T 细胞自身抗原。
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