StC Sinclair N R
Transplant Proc. 1978 Jun;10(2):349-53.
Biologically important regulatory mechanisms exist in many immune responses. The anatomic characteristics of lymphoid tissues and the cell-collaborative events exhibited in immune responses may be explicable in terms of potent regulatory phenomena rather than or as well as requirements for the initial activation of an immune response by antigen. Mechanistically, the regulatory web54 may be a series of Fc portion attachments to Fc receptors directed by the variable region specificities of the antibodies involved.
许多免疫反应中存在具有生物学重要性的调节机制。淋巴组织的解剖学特征以及免疫反应中表现出的细胞协作事件，或许可以用有效的调节现象来解释，而非仅归因于抗原对免疫反应的初始激活需求，或者也可以说部分归因于此。从机制上讲，调节网络54可能是由相关抗体可变区特异性所引导的一系列Fc部分与Fc受体的附着。
