Galica Adelina Nicoleta, Galica Reitano, Dumitrașcu Dan Lucian
2 Department of Internal Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
Department of Nursing, Faculty of Natural and Human Sciences, Fan S. Noli University, Korçe, Albania.
J Med Life. 2022 Feb;15(2):174-179. doi: 10.25122/jml-2022-0028.
Many aspects make irritable bowel syndrome (IBS) challenging for both patients and physicians. The unclear pathogenesis with many pathways to be explored, bothering symptoms that affect the quality of life, and many subtypes of the condition are only a few reasons that make IBS difficult to control and obtain satisfactory results. Treatment options start with general advice for lifestyle, continue with non-pharmaceutical treatments, and finally touch classic treatments. In this review, pharmaceutical treatment options are not accounted for. Consensus groups and meta-analyses have concluded guidelines that overall are the same, with variations in the strength of recommendations and some cultural and geographical particularities. Dietary interventions, probiotics, and fibers can be seen as non-pharmaceutical treatments that coexist in various protocols because of the relevant evidence regarding their efficacy in treating IBS symptoms.
肠易激综合征(IBS)在诸多方面给患者和医生都带来了挑战。其发病机制尚不明确,有许多途径有待探索;恼人的症状影响生活质量;而且该病症有多种亚型,这些只是导致IBS难以控制并取得满意疗效的部分原因。治疗方案首先是一般的生活方式建议,接着是非药物治疗,最后才是传统治疗。在本综述中,未涉及药物治疗方案。共识小组和荟萃分析得出的指南总体上是一致的,只是在推荐强度上有所差异,还有一些文化和地域特点。饮食干预、益生菌和膳食纤维可被视为非药物治疗方法,由于有关于它们治疗IBS症状有效性的相关证据,所以在各种方案中并存。