Mansour Omar T, Venero Diego Alba
Leicester School of Pharmacy, Faculty of Health and Life Sciences, De Montfort University The Gateway Leicester Leicestershire LE1 9BH UK
ISIS Neutron and Muon Source, Science and Technology Facilities Council, Rutherford Appleton Laboratory Didcot Oxfordshire OX11 0QX UK.
RSC Adv. 2021 Apr 16;11(24):14306-14313. doi: 10.1039/d1ra00755f. eCollection 2021 Apr 15.
Sunscreen lotions and creams are arguably the most popular products used to protect the skin against harmful UV radiation. Several studies have been conducted to untangle the internal microstructure of creams and lotions. However, the effect of UV filters and other materials such as preservatives, on the internal microstructure and the aesthetics of these products is not yet fully understood. Using small-angle neutron scattering (SANS), we were able to investigate the effect of adding the commonly used organic UV filters (avobenzone (AVB), ethylhexyl methoxycinnamate (EMC), ethylhexyl triazone (EHT) and bemotrizinol (BMT)) and the water soluble preservatives (1,5-pentanediol (1,5-PD) and 1,2-hexanediol (1,2-HD)), on the internal architecture and microstructure of an oil-in-water (o/w) based sunscreen lotion. Our findings highlight the complexities of these formulations, and how the introduction of different additives could influence their structure and possibly their performance.
防晒霜乳液和面霜可以说是用于保护皮肤免受有害紫外线辐射的最受欢迎的产品。已经进行了几项研究来解开面霜和乳液的内部微观结构。然而，紫外线过滤剂和其他材料（如防腐剂）对这些产品的内部微观结构和美观度的影响尚未完全了解。通过小角中子散射（SANS），我们能够研究添加常用的有机紫外线过滤剂（阿伏苯宗（AVB）、甲氧基肉桂酸乙基己酯（EMC）、乙基己基三嗪酮（EHT）和倍他米松（BMT））以及水溶性防腐剂（1,5-戊二醇（1,5-PD）和1,2-己二醇（1,2-HD））对水包油（o/w）型防晒霜乳液的内部结构和微观结构的影响。我们的研究结果突出了这些配方的复杂性，以及不同添加剂的引入如何影响它们的结构以及可能的性能。
