Skotarczak K, Osmola-Mańkowska A, Lodyga M, Polańska A, Mazur M, Adamski Z
Faculty of Pharmacy, Specialisation Cosmetology, Poznan University of Medical Sciences, Poznan, Poland.
Eur Rev Med Pharmacol Sci. 2015 Jan;19(1):98-112.
Excessive exposure of the skin to sunlight can lead to many negative effects, such as sunburn, photoaging and skin cancer development. Pollution and stratospheric ozone layer depletion are factors that increase exposure to ultraviolet radiation. This work is an accurate summary of the current state of knowledge on broad-spectrum photoprotection. Avoiding the sun, skin protection through the use of protective clothing and protective filters are currently the most effective methods of sunscreen provided that they are suitably used. In addition, discussed are controversial issues such as the toxicity of zinc used in sunscreen preparations and the potential for deficiency of vitamin D3 in relation with the application of strict photoprotection. The study has also addressed issues concerning the most recent lines of research in the exploration of modern methods of photoprotection both local and systemic, such as with the use of photolyase or examination of various enzymes repairing damage after sun exposure, as well as the promising future in photoprotection technology.
皮肤过度暴露于阳光下会导致许多负面影响，如晒伤、光老化和皮肤癌的发生。污染和平流层臭氧层损耗是增加紫外线辐射暴露的因素。这项工作是对广谱光保护当前知识状态的准确总结。避免日晒、通过使用防护服和防护滤光片进行皮肤保护，只要使用得当，目前是最有效的防晒方法。此外，还讨论了一些有争议的问题，如防晒制剂中使用的锌的毒性以及与严格光保护应用相关的维生素D3缺乏的可能性。该研究还探讨了有关探索局部和全身光保护现代方法的最新研究方向的问题，例如使用光解酶或检测日晒后修复损伤的各种酶，以及光保护技术的光明未来。
