Khilji Hamza, Silver Caroline, Morrar Doaa, Chhabra Arpit M, Mandel Steven, Langer David J, Shani Dana, Ellis Jason A
Neurosurgery, Lenox Hill Hospital/Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, USA.
Hematology-Oncology, Lenox Hill Hospital/Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, USA.
Cureus. 2022 Mar 13;14(3):e23130. doi: 10.7759/cureus.23130. eCollection 2022 Mar.
Cranial solitary plasmacytomas are uncommon lesions, and localization to the skull base is rare. Here we present a case in a 36-year-old woman who complained of dizziness and mild headaches. Radiographic imaging indicated the presence of a solitary skull base lesion in the posterior cranial fossa. Laboratory tests and imaging excluded systemic disease. A biopsy of the lesion confirmed the diagnosis of plasmacytoma. The patient was treated with proton-beam radiation and had a complete clinical and radiographic resolution, demonstrating the previously unreported utility of monotherapy with proton-beam radiation in such cases.
颅骨孤立性浆细胞瘤是一种罕见的病变，而累及颅底的情况更为罕见。在此，我们报告一例36岁女性患者，她主诉头晕和轻度头痛。影像学检查显示后颅窝存在一个孤立的颅底病变。实验室检查和影像学检查排除了全身性疾病。病变活检确诊为浆细胞瘤。该患者接受了质子束放疗，临床和影像学表现完全缓解，这表明质子束放疗单药治疗在此类病例中的疗效此前尚未见报道。
