Nursyifa Fadiyah Nanda, Megawati Ginna, Erlangga Luftimas Dimas
Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
Department of Public Health, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia.
Int J Gen Med. 2022 Apr 11;15:3915-3922. doi: 10.2147/IJGM.S357460. eCollection 2022.
COVID-19 can cause fever, cough, headache, and shortness of breath but patients with comorbidities can experience worsening and death. An action is needed to treat this condition in COVID-19 patients. Omega 3 fatty acids may be one possibility associated with COVID-19 prevention, management, and treatment. Therefore, this review aimed to identify the existing studies on potency of omega 3 fatty acid supplementation on COVID-19. We searched studies from PubMed, Google Scholar, Springer Link, and Emerald Insight databases published on January 31, 2020, to September 1, 2021. The studies selected were the full-text, non-review ones which focused on the omega 3 fatty acid intervention in COVID-19 with COVID-19 patients and people affected by COVID-19 as their subjects and clinical manifestations or the results of supporting examinations as their outcomes. No quality assessment was performed in this review. Of the 211, there were 4 studies selected for this review. They showed that severe COVID-19 patients have low levels of omega 3 in their blood. Omega 3 was considered to reduce the risk of positive for SARS-CoV-infection and the duration of symptoms, overcome the renal and respiratory dysfunction, and increase survival rate in COVID-19 patients. Omega 3 fatty acid supplementations were thought to have a potential effect in preventing and treating COVID-19. This can be a reference for further research about omega 3 fatty acid supplementation and COVID-19.
新型冠状病毒肺炎可引起发热、咳嗽、头痛和呼吸急促,但合并症患者可能病情加重甚至死亡。需要采取行动治疗新型冠状病毒肺炎患者的这种情况。欧米伽3脂肪酸可能是与新型冠状病毒肺炎预防、管理和治疗相关的一种可能性。因此,本综述旨在确定关于补充欧米伽3脂肪酸对新型冠状病毒肺炎疗效的现有研究。我们检索了2020年1月31日至2021年9月1日在PubMed、谷歌学术、施普林格链接和Emerald Insight数据库上发表的研究。所选研究为全文、非综述性研究,其聚焦于以新型冠状病毒肺炎患者和受新型冠状病毒肺炎影响的人群为对象,以新型冠状病毒肺炎中的欧米伽3脂肪酸干预以及临床表现或辅助检查结果为结局。本综述未进行质量评估。在211项研究中,有4项被选入本综述。这些研究表明,新型冠状病毒肺炎重症患者血液中的欧米伽3水平较低。欧米伽3被认为可降低感染严重急性呼吸综合征冠状病毒呈阳性的风险和症状持续时间,克服肾脏和呼吸功能障碍,并提高新型冠状病毒肺炎患者的生存率。补充欧米伽3脂肪酸被认为在预防和治疗新型冠状病毒肺炎方面具有潜在作用。这可为进一步研究补充欧米伽3脂肪酸与新型冠状病毒肺炎提供参考。