Suppr超能文献

预测患有精神疾病诊断的青少年父母未解决风险的列线图的开发与验证

Development and Validation of a Nomogram for Predicting the Unresolved Risk of Parents of Adolescents With Psychiatric Diagnoses.

作者信息

Sheng Qingqing, Cai Chunfeng, Li Pingdong, Chen Lihua, Zhang Xi, Wang Xinyu, Gong Yucui

机构信息

Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.

School of Health Sciences, Wuhan University, Wuhan, China.

出版信息

Front Psychiatry. 2022 Apr 1;13:796384. doi: 10.3389/fpsyt.2022.796384. eCollection 2022.

Abstract

Evaluating the resolution of parents of ill children can help in taking measures to alleviate their distress in a timely manner and promote children's rehabilitation. This study aims to develop and validate a nomogram for predicting the unresolved risk of parents of adolescents with psychiatric diagnoses. The data for 130 parents (modeling dataset = 90; validation dataset = 40) were collected. A nomogram was first developed to predict the unresolved risk for parents based on the logistic regression analysis in the modeling dataset. The internal and external validation then were conducted through quantifying the performance of the nomogram with respect to discrimination and calibration, respectively, in the modeling and validation datasets. Finally, the clinical use was evaluated through decision curve analyses (DCA) in the overall dataset. In the results, the nomogram consisted of six risk factors and provided a good discrimination with areas under the curve of 0.920 (95% , 0.862-0.978) in internal validation and 0.886 (95% , 0.786-0.986) in external validation. The calibration with good consistency between the observed probability and predicted probability was also found in both internal and external validation. DCA showed that the nomogram had a good clinical utility. In conclusion, the proposed nomogram exhibited a favorable performance with regard to its predictive accuracy, discrimination capability, and clinical utility, and, thus, can be used as a convenient and reliable tool for predicting the unresolved risk of parents of children with psychiatric diagnoses.

摘要

评估患病儿童父母的心理调适状况有助于及时采取措施减轻他们的痛苦,并促进儿童的康复。本研究旨在开发并验证一个列线图,用于预测患有精神疾病诊断的青少年父母心理调适未解决的风险。收集了130名父母的数据(建模数据集 = 90;验证数据集 = 40)。首先基于建模数据集中的逻辑回归分析开发了一个列线图,用于预测父母心理调适未解决的风险。然后分别通过在建模数据集和验证数据集中量化列线图在区分度和校准方面的表现进行内部和外部验证。最后,通过在整个数据集中进行决策曲线分析(DCA)来评估其临床应用价值。结果显示,该列线图由六个风险因素组成,内部验证时曲线下面积为0.920(95%,0.862 - 0.978),外部验证时为0.886(95%,0.786 - 0.986),具有良好的区分度。在内部和外部验证中还发现观察概率与预测概率之间具有良好一致性的校准。DCA表明该列线图具有良好的临床应用价值。总之,所提出的列线图在预测准确性、区分能力和临床应用价值方面表现良好,因此可作为一种方便可靠的工具,用于预测患有精神疾病诊断儿童的父母心理调适未解决的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bda/9010732/cabf84fa5b7a/fpsyt-13-796384-g0001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验