The School of Nursing, Anhui University of Chinese Medicine, Hefei, China.
The Second Clinical Medical School, Guangzhou University of Chinese Medicine Guangzhou, China.
J Clin Nurs. 2023 Jun;32(11-12):2399-2409. doi: 10.1111/jocn.16325. Epub 2022 Apr 17.
To compare and rank the effectiveness of non-pharmacological interventions for symptoms of Overactive Bladder (OAB) in network meta-analysis.
Overactive Bladder affects many patients, which often generates bothersome symptoms and debilitates the quality of life. Non-pharmacological therapies have been widely used in OAB. However, due to insufficient evidence, it remains unclear which strategies are most suitable for OAB.
We integrated randomised controlled trials (RCTs), which were searched up to 1 January 2021, from 8 databases (PubMed, Embase, Cochrane library, Web of Science, China National Knowledge Infrastructure, Wanfang Database, VIP Database, and China Biology Medicine disc). Studies that met the eligible criteria were assessed the risk of bias. Then, network meta-analyses were conducted by STATA, R, and OpenBUGS. The review followed PRISMA statement.
A total of 24 studies comprising 2347 patients with OAB were included in this review, most of which were low to moderate risk of bias. The results of network meta-analysis implied that electric stimulation (ES) was the most effective intervention to reduce voided frequency and nocturia frequency of OAB.
Electric stimulation ranked the best in the management of OAB, and future studies should pay more attention to ES.
通过网络荟萃分析比较和排列非药物干预治疗膀胱过度活动症（OAB）症状的有效性。
膀胱过度活动症影响许多患者，常产生令人困扰的症状，并降低生活质量。非药物治疗已广泛应用于 OAB。然而，由于证据不足，哪种策略最适合 OAB 仍不清楚。
我们整合了截至 2021 年 1 月 1 日从 8 个数据库（PubMed、Embase、Cochrane 图书馆、Web of Science、中国知网、万方数据库、维普数据库和中国生物医学文献数据库）搜索到的随机对照试验（RCT）。符合入选标准的研究被评估了偏倚风险。然后，使用 STATA、R 和 OpenBUGS 进行网络荟萃分析。本综述遵循 PRISMA 声明。
本综述共纳入了 24 项研究，涉及 2347 例 OAB 患者，其中大多数研究的偏倚风险为低至中度。网络荟萃分析的结果表明，电刺激（ES）是减少 OAB 排尿频率和夜尿频率最有效的干预措施。
电刺激在 OAB 的管理中排名最佳，未来的研究应更多地关注 ES。
