Gerdes Christoph, Neesse Albrecht
Klinik für Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule Hannover, Deutschland.
Klinik für Gastroenterologie, gastrointestinale Onkologie und Endokrinologie, Universitätsmedizin Göttingen, Georg-August-Universität, Göttingen, Deutschland.
Ther Umsch. 2022 Apr;79(3-4):209-211. doi: 10.1024/0040-5930/a001350.
Acute Diseases of the Esopagus - Esophagitis Inflammation of the esophagus can be caused by various conditions including gastroesophageal reflux (GERD), immunosuppression, infections, allergens, or distinct medications. GERD will be covered in a separate article. Clinical symptoms include heartburn, retrosternal pain, dysphagia, or fetor ex ore. Bleeding, strictures, or stenoses can occur as local complications. Besides a detailed medical history, diagnostic tools are usually an accurate physical examination and flexible endoscopy including histological and microbiological sampling. Immunosuppressive drugs, HIV, malignancies, and chronic alcohol abuse are often associated with candida esophagitis which is typically treated with fluconazole. History of allergies is especially relevant for eosinophilic esophagitis (EoE) which mostly affects young patients and can be treated with topical steroids. A rare but important differential diagnosis to EoE is esophageal lichen planus.
食管急性疾病——食管炎 食管炎症可由多种情况引起,包括胃食管反流(GERD)、免疫抑制、感染、过敏原或特定药物。GERD将在另一篇文章中讨论。临床症状包括烧心、胸骨后疼痛、吞咽困难或口臭。出血、狭窄或狭窄可作为局部并发症出现。除了详细的病史外,诊断工具通常是准确的体格检查和包括组织学和微生物学采样的柔性内镜检查。免疫抑制药物、HIV、恶性肿瘤和慢性酒精滥用常与念珠菌性食管炎有关,通常用氟康唑治疗。过敏史对嗜酸性食管炎(EoE)尤为重要,EoE主要影响年轻患者,可用局部类固醇治疗。EoE一种罕见但重要的鉴别诊断是食管扁平苔藓。