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下颌骨原发性单相滑膜肉瘤的分子学确认:诊断与治疗。

Molecular confirmation of primary monophasic synovial sarcoma of the mandible: diagnosis and management.

机构信息

Department of Oral and Maxillofacial Surgery, University Hospital Galway, Galway, Ireland.

Department of Histopathology, University Hospital Galway, Galway, Ireland.

出版信息

Br J Oral Maxillofac Surg. 2022 Sep;60(7):994-996. doi: 10.1016/j.bjoms.2022.02.004. Epub 2022 Feb 23.

DOI:10.1016/j.bjoms.2022.02.004
PMID:35440394
Abstract

Synovial sarcoma (SS) is a rare, high-grade, soft tissue malignancy that originates from pluripotent mesenchymal stem cells. Knox introduced the term 'synovial sarcoma', noting its histological similarity to synovial tissue. SS is seen most frequently in young and middle-aged adults with an equal sex distribution. Symptoms are non-specific and relate to the local effect of the mass. Currently, we know of no specific guidelines for the management of SS in the head and neck. We report a case of primary monophasic SS of the mandible in a 59-year-old male, and outline our diagnostic approach and management.

摘要

滑膜肉瘤(SS)是一种罕见的、高级别的软组织恶性肿瘤,起源于多能间充质干细胞。Knox 提出了“滑膜肉瘤”一词,指出其组织学与滑膜组织相似。SS 最常见于年轻和中年成年人,男女发病率相等。症状不具有特异性,与肿块的局部影响有关。目前,我们还没有针对头颈部 SS 的具体管理指南。我们报告了一例 59 岁男性下颌原发性单相滑膜肉瘤,并概述了我们的诊断方法和治疗方案。

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