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未能触诊成年高血压患者的股动脉搏动可能导致诊断迷失,并在未检测到主动脉缩窄的情况下导致主要脑血管事件。

Failing to palpate femoral pulses in adult hypertensive patients may lead to diagnostic wandering and major cerebrovascular events in cases of undetected aortic coarctation.

机构信息

Université de Paris Cité, AP-HP, Hôpital Lariboisière, Physiologie Clinique - Explorations Fonctionnelles, Hypertension Unit, F-75010, Paris, France.

Université de Paris Cité, INSERM UMR1148 - LVTS, Hôpital Bichat, F-75018, Paris, France.

出版信息

J Hum Hypertens. 2022 Jul;36(7):689-692. doi: 10.1038/s41371-022-00687-9. Epub 2022 Apr 19.

DOI:10.1038/s41371-022-00687-9
PMID:35440761
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9287169/
Abstract

In developed countries, aortic coarctation (AC) is generally diagnosed by fetal echocardiography during the third trimester of pregnancy, or during the neonatal period based on the absence of femoral pulses or the presence of a left supraclavicular systolic murmur. However, AC may be diagnosed late, such as in adult migrants arriving from developing countries without documented medical history although they may require healthcare support during their stay. We report three cases of the incidental diagnosis of thoracic aortic malformations in adults (27, 38 and 43 years) referred for the management of uncontrolled high blood pressure, with major cerebrovascular events for the two oldest. Doppler ultrasound imaging indicated for suspected renal artery stenosis and atheroma lesions revealed abnormal lower-body and normal upper-body arterial blood flow velocity waveforms constitutive of a pathognomonic hemodynamic pattern of AC, a diagnostic which was in all three cases confirmed by multidetector computed tomography-angiography. None of these patients had undergone complete cardiovascular examination, particularly with effective peripheral pulse palpation, during the period preceding the occurrence of major cardiovascular events or at any other time after birth. Our observation suggests that a simple medical examination could have prevented diagnostic wandering and, possibly, the occurrence of severe cerebrovascular complications in two of these three patients.

摘要

在发达国家,主动脉缩窄(AC)通常在妊娠晚期通过胎儿超声心动图诊断,或在新生儿期根据股动脉搏动缺失或左锁骨上收缩期杂音的存在来诊断。然而,AC 可能会被延迟诊断,例如来自发展中国家的成年移民,他们虽然在逗留期间可能需要医疗保健支持,但没有记录在案的病史。我们报告了三例在成人中偶然诊断出的胸主动脉畸形的病例(27、38 和 43 岁),这些病例因未控制的高血压而接受治疗,其中两名最年长的患者发生了重大脑血管事件。对疑似肾动脉狭窄和动脉粥样硬化病变进行的多普勒超声成像显示,异常的下半身和正常的上半身动脉血流速度波形构成了 AC 的特征性血流动力学模式,所有这三个病例均通过多排 CT 血管造影得到了诊断。这些患者在发生重大心血管事件之前或出生后任何时候都没有接受过完整的心血管检查,特别是没有进行有效的外周脉搏触诊。我们的观察表明,简单的体格检查本可以避免诊断上的困惑,并可能防止这三个患者中的两个人发生严重的脑血管并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e8/9287169/61314287231a/41371_2022_687_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e8/9287169/61314287231a/41371_2022_687_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e8/9287169/61314287231a/41371_2022_687_Fig1_HTML.jpg

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Failing to palpate femoral pulses in adult hypertensive patients may lead to diagnostic wandering and major cerebrovascular events in cases of undetected aortic coarctation.未能触诊成年高血压患者的股动脉搏动可能导致诊断迷失,并在未检测到主动脉缩窄的情况下导致主要脑血管事件。
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Int Heart J. 2018 Nov 28;59(6):1340-1345. doi: 10.1536/ihj.17-564. Epub 2018 Oct 10.
3
A Case of Uncorrected Tetralogy of Fallot Undiagnosed Until Adulthood and Presenting With Polycythemia.一例成年期才被诊断出的未经矫治的法洛四联症并伴有红细胞增多症
Cardiol Res. 2014 Dec;5(6):198-200. doi: 10.14740/cr374e. Epub 2014 Dec 4.
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Risk Factors for Coarctation of the Aorta on Prenatal Ultrasound: A Systematic Review and Meta-Analysis.胎儿超声检查主动脉缩窄的危险因素:系统评价和荟萃分析。
Circulation. 2017 Feb 21;135(8):772-785. doi: 10.1161/CIRCULATIONAHA.116.024068. Epub 2016 Dec 29.
5
Aortic coarctation repair in the adult.成人主动脉缩窄修复术
J Card Surg. 2014 Jul;29(4):512-8. doi: 10.1111/jocs.12367. Epub 2014 Jun 3.
6
Variants in the NOTCH1 gene in patients with aortic coarctation.主动脉缩窄患者NOTCH1基因的变异
Congenit Heart Dis. 2014 Sep-Oct;9(5):391-6. doi: 10.1111/chd.12157. Epub 2014 Jan 12.
7
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Turk Kardiyol Dern Ars. 2012 Jan;40(1):66-8. doi: 10.5543/tkda.2012.01689.
8
Interrupted aortic arch in the adult.成人主动脉弓中断
J Card Surg. 2011 Jul;26(4):405-9. doi: 10.1111/j.1540-8191.2011.01273.x.
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J Vasc Surg. 2010 Jun;51(6):1550-9. doi: 10.1016/j.jvs.2009.12.063. Epub 2010 Mar 11.