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中国重庆短期 PM 暴露与痤疮门诊就诊的关系:一项时间序列研究。

The relationship between short-term PM exposure and outpatient visits for acne vulgaris in Chongqing, China: a time-series study.

机构信息

Department of Epidemiology, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038, China.

Department of Plastic & Cosmetic Surgery, Daping Hospital, Army Medical University (Third Military Medical University), Chongqing, 400042, China.

出版信息

Environ Sci Pollut Res Int. 2022 Aug;29(40):61502-61511. doi: 10.1007/s11356-022-20236-8. Epub 2022 Apr 20.

Abstract

Many researches have reported the air pollution impacts, either long term or short term, on inflammatory skin diseases, but there are few studies on the relation between PM and acne vulgaris. To determine the correlation between short-term PM exposure and acne outpatient visits, data for 120,842 acne vulgaris outpatient visits between December 2013 and December 2019 were obtained from three large hospitals in Chongqing, China. Both single-pollutant models and two-pollutant models were established to explore the relationship between PM exposure and acne outpatient visits. The stratified analyses were conducted through two-sample z-tests to investigate the possible gender (male or female) and age (< 25 years or ≥ 25 years) differences in PM effects. The results demonstrated positive correlations between PM concentrations and acne outpatient visits. A 10 μg/m increase in PM concentration was associated with a 1.71% (95% CI: 1.06-2.36%) increase in acne outpatient visits at lag 0-7 day. Stratified analyses showed that PM effects were greater in individuals aged ≥ 25 years than those aged < 25 years, but no gender difference was found. In conclusion, short-term PM exposure was positively associated with the risk of acne outpatient visits, especially for people ≥ 25 years old.

摘要

许多研究报告了空气污染对炎症性皮肤病的长期或短期影响,但关于 PM 与寻常痤疮之间的关系的研究较少。为了确定短期 PM 暴露与痤疮门诊就诊之间的相关性,我们从中国重庆的三家大医院获取了 2013 年 12 月至 2019 年 12 月期间 120842 例痤疮门诊就诊的数据。我们建立了单污染物模型和双污染物模型来探索 PM 暴露与痤疮门诊就诊之间的关系。通过两样本 z 检验进行分层分析,以调查 PM 效应中可能存在的性别(男性或女性)和年龄(<25 岁或≥25 岁)差异。结果表明,PM 浓度与痤疮门诊就诊之间存在正相关关系。PM 浓度每增加 10μg/m,在滞后 0-7 天内,痤疮门诊就诊的风险增加 1.71%(95%CI:1.06-2.36%)。分层分析表明,PM 效应在年龄≥25 岁的个体中大于年龄<25 岁的个体,但未发现性别差异。总之,短期 PM 暴露与痤疮门诊就诊的风险呈正相关,尤其是对于年龄≥25 岁的人群。

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