他莫昔芬和芳香化酶抑制剂均不会增加英国生物库队列中帕金森病的风险。
Neither tamoxifen nor aromatase inhibitors increase the risk of Parkinson disease in the UK Biobank cohort.
机构信息
Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York.
Severn Health Solutions, Severna Park, Maryland.
出版信息
Cancer. 2022 Aug 1;128(15):2997-2998. doi: 10.1002/cncr.34245. Epub 2022 Apr 20.
Abstract
Treatment with aromatase inhibitors (AIs) or tamoxifen does not increase the risk of Parkinson’s Disease (PD) in women with breast cancer. The insignificant increase in PD associated with AIs on univariate analysis is an age effect, that is, older women are more likely to receive AIs and more likely to develop PD.
摘要
使用芳香化酶抑制剂（AIs）或他莫昔芬治疗不会增加乳腺癌女性患帕金森病（PD）的风险。单因素分析中与 AIs 相关的 PD 发生率增加无统计学意义，这是一种年龄效应，即老年女性更有可能接受 AIs 治疗，并且更有可能发生 PD。
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