Division of Allergy/Clinical Immunology, Medical College of Wisconsin, Milwaukee, Wisconsin,
WMJ. 2022 Apr;121(1):48-53.
Hereditary angioedema (HAE) is a rare and disabling disorder wherein there is excessive bradykinin production, with subsequent increased vascular permeability in the superficial tissues and gastrointestinal and respiratory mucosa. This article serves as a review of the pathogenesis of the disease, as well as an update of the evidence-based new treatment recommendations to help clinicians with the diagnosis and management of HAE.
遗传性血管性水肿（HAE）是一种罕见且使人丧失能力的疾病，其特征是缓激肽产生过多，随后导致浅表组织和胃肠道及呼吸道黏膜的血管通透性增加。本文旨在回顾该疾病的发病机制，并更新基于循证的新治疗建议，以帮助临床医生诊断和管理 HAE。
