Controlled Environment Systems Research Facility, University of Guelph, Guelph, Ontario, Canada.
Int J Med Mushrooms. 2022;24(1):1-11. doi: 10.1615/IntJMedMushrooms.2021041921.
Psilocybin is a psychoactive alkaloid that is produced naturally by approximately 200 species of mushrooms. The potential medical use of this molecule for the treatment of mental illness is gaining renewed momentum. As demand grows and clinical trials progress, appropriate methods for producing a quality pharmaceutical product are needed. This review highlights the methods currently available, such as the prominent synthetic method and its biosynthetic alternatives, as well as others on the near horizon. This article further seeks to discuss the rapid and evolving nature of the psilocybin industry in the 21st century.
裸盖菇素是一种精神活性生物碱，大约有 200 种蘑菇天然产生这种物质。这种分子在治疗精神疾病方面的潜在医学用途正在重新受到关注。随着需求的增长和临床试验的推进，需要有合适的方法来生产高质量的药物产品。这篇综述强调了目前可用的方法，如突出的合成方法及其生物合成替代品，以及其他即将出现的方法。本文还进一步探讨了 21 世纪裸盖菇素行业快速发展的特点。
