Honyiglo Emma, Franchi Angélique, Cartiser Nathalie, Bottinelli Charline, Advenier Anne-Sophie, Bévalot Fabien, Fanton Laurent
Forensic Medicine Department, University Hospital of Lyon, 5 place d'Arsonval, Lyon, France.
Faculty of Medicine, University of Lyon, UCBL1, 8 avenue Rockefeller, Lyon, France.
J Forensic Sci. 2019 Jul;64(4):1266-1270. doi: 10.1111/1556-4029.13982. Epub 2018 Dec 12.
Fatalities implicating psychedelic mushrooms are not a common clinical situation in everyday forensic medicine. Despite classification as an illegal drug in many countries, psilocybin mushrooms have the reputation of being safe. We report the case of a young man who jumped from a second story balcony under the influence of psilocybin mushrooms. The psilocin assay was performed by gas chromatography coupled to an electron-impact ionization time-of-flight detector (GC-EI-TOF) after solid-phase extraction. Total psilocin was quantified in peripheral and cardiac blood as 60 and 67 ng/mL, respectively, and in urine (2230 ng/mL), bile (3102 ng/mL), and vitreous humor (57 ng/mL). This case report and review of literature highlights the danger of psilocybin mushrooms. Isolated use of psilocybin mushrooms by a regular consumer without psychiatric history, even under "safe" circumstances, can lead to a fatal outcome.
在日常法医学中，涉及致幻蘑菇的死亡案例并非常见的临床情况。尽管在许多国家被列为非法药物，但裸盖菇素蘑菇素有安全的声誉。我们报告了一名年轻男子在裸盖菇素蘑菇的影响下从二楼阳台跳下的案例。通过固相萃取后，采用气相色谱-电子轰击电离飞行时间检测器（GC-EI-TOF）进行裸盖菇素测定。外周血和心脏血中总裸盖菇素的定量分别为60和67 ng/mL，尿液中为2230 ng/mL，胆汁中为3102 ng/mL，玻璃体液中为57 ng/mL。本病例报告及文献综述凸显了裸盖菇素蘑菇的危险性。即使在“安全”情况下，无精神病史的普通消费者单独使用裸盖菇素蘑菇也可能导致致命后果。
