J Am Vet Med Assoc. 2022 May 21;260(S2):S64-S71. doi: 10.2460/javma.22.02.0071.
Urolithiasis is the most common cause of urinary tract disease in small ruminants and has significant economic and production impacts worldwide. Urolithiasis is multifactorial in origin and generally begins with the formation of cystoliths followed by urethral obstruction. The condition is most common in males. Clinical signs are variable depending on the severity of the obstruction. Uroliths can be calcium, struvite, or silicate based; however, struvite and amorphous magnesium calcium phosphate are the most common urolith types observed in small ruminants. Although urethral process (vermiform appendage) amputation is widely considered the first line of treatment, reobstruction is common within the first 36 hours. Surgical interventions such as temporary tube cystostomy, perineal urethrostomy (PU), modified proximal perineal urethrostomy, vesico-preputial anastomosis (VPA), and urinary bladder marsupialization (BM) are reported to carry an improved prognosis for long-term survival. PU carries a lower proportion of long-term success (> 12-month survival time) when compared with VPA and BM. Stoma stricture and urine scald are the most commonly observed surgical complications. Currently, the literature provides minimal direction for clinician decision-making in managing these cases while accounting for patient history, client financial ability, composition of calculi, and potential treatment complications. Small ruminant urinary obstructions are challenging and complicated conditions to treat, due to their multifactorial etiology, ruminant urogenital anatomy, and the variety of imperfect treatment options available. The purpose of this article this article is to provide veterinary practitioners with decision trees to guide management and treatment of urolithiasis in small ruminants.
尿石症是小反刍动物中最常见的尿路疾病病因,对全球的经济和生产都有重大影响。尿石症的病因是多因素的,通常始于胱氨酸结石的形成,随后发生尿道梗阻。该病在雄性中更为常见。临床症状的严重程度取决于梗阻的严重程度。尿石可以是钙基、鸟粪石或硅酸盐基的;然而,鸟粪石和非晶态磷酸镁钙是小反刍动物中最常见的尿石类型。虽然尿道过程(蚓状附肢)切除术被广泛认为是一线治疗方法,但在最初的 36 小时内再次梗阻很常见。外科干预,如临时管膀胱造口术、会阴尿道造口术(PU)、改良近端会阴尿道造口术、膀胱-包皮吻合术(VPA)和膀胱袋状造口术(BM),被报道对长期生存预后有改善作用。与 VPA 和 BM 相比,PU 的长期成功率(>12 个月的存活时间)较低。造口狭窄和尿液烫伤是最常见的手术并发症。目前,文献对临床医生在管理这些病例时的决策提供了很少的指导,同时考虑了患者病史、客户的财务能力、结石成分和潜在的治疗并发症。小反刍动物尿道梗阻是一种具有挑战性且复杂的疾病,因为其病因多因素、反刍动物泌尿生殖解剖结构以及可用的治疗方法不完善。本文的目的是为兽医从业者提供决策树,以指导小反刍动物尿石症的管理和治疗。