Emily Lorang, Jinkuk Hong, Leann Smith DaWalt, and Marsha Mailick, University of Wisconsin-Madison.
Am J Intellect Dev Disabil. 2022 May 1;127(3):231-248. doi: 10.1352/1944-7558-127.3.231.
This study investigated the bidirectional effects of change in maladaptive behaviors among adolescents and adults with fragile X syndrome (FXS) and change in their intergenerational family relationships over a 7.5-year period. Indicators of the intergenerational family relationship between premutation carrier mothers and their adolescent or adult son/daughter with FXS included a measure of the quality of the relationship, as well as descriptions provided by mothers of their relationship with their son/daughter (positive remarks, critical remarks). Maladaptive behaviors decreased, maternal positive remarks increased, and maternal critical remarks and relationship quality remained stable over time. Bidirectional effects of change were observed in predicting maladaptive behaviors and maternal positive remarks, although maladaptive behaviors more strongly predicted positive remarks than the reciprocal association. This research suggests prioritizing maladaptive behaviors in the context of family interventions.
本研究调查了脆性 X 综合征（FXS）青少年和成年人的适应不良行为变化与他们的代际家庭关系变化之间在 7.5 年期间的双向影响。脆性 X 综合征先证者携带者母亲与其青少年或成年儿子/女儿之间代际家庭关系的指标包括关系质量的衡量标准，以及母亲对其与儿子/女儿关系的描述（积极评价、批评评价）。适应不良行为减少，母亲的积极评价增加，而母亲的批评评价和关系质量随着时间的推移保持稳定。变化的双向影响在预测适应不良行为和母亲的积极评价方面都有观察到，尽管适应不良行为对积极评价的预测作用强于相互关系。这项研究表明，在家庭干预中应优先考虑适应不良行为。
