人类白细胞抗原表型与药物引起的大疱性皮肤反应。
HLA phenotypes and bullous cutaneous reactions to drugs.
作者信息
Roujeau J C, Bracq C, Huyn N T, Chaussalet E, Raffin C, Duédari N
出版信息
Tissue Antigens. 1986 Oct;28(4):251-4. doi: 10.1111/j.1399-0039.1986.tb00491.x.
Abstract
Drug induced toxic epidermal necrolysis and Stevens-Johnson syndrome are weakly associated with HLA-B12. Among patients reacting to a given drug we observed stronger links, especially for HLA-A29; B12; DR7 and sulphonamides.
摘要
药物性中毒性表皮坏死松解症和史蒂文斯-约翰逊综合征与HLA - B12的关联较弱。在对特定药物有反应的患者中，我们观察到更强的联系，特别是对于HLA - A29、B12、DR7和磺胺类药物。
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