Oloo A J, Kamunvi F, Owaga M L
Trans R Soc Trop Med Hyg. 1986;80(4):532-3. doi: 10.1016/0035-9203(86)90132-x.
The sensitivity of Plasmodium falciparum to chloroquine was studied in 140 children in two locations in Western Kenya. The standard WHO in vivo field test was used and chloroquine phosphate 25 mg base/kg administered in divided doses over three days. In one area 13.2% of cases had recrudescent parasitaemias, while in the other area 8.2% of infections were resistant, with 3.5% having an RII pattern. The remaining isolates were sensitive to chloroquine. Further in vivo and in vitro tests in the region are needed to document the extent and level of resistance.
在肯尼亚西部的两个地点，对140名儿童体内的恶性疟原虫对氯喹的敏感性进行了研究。采用了世界卫生组织的标准体内现场试验，按25毫克碱基/千克的磷酸氯喹分剂量在三天内给药。在一个地区，13.2%的病例出现了复发性寄生虫血症，而在另一个地区，8.2%的感染具有抗性，其中3.5%呈现RII模式。其余分离株对氯喹敏感。该地区需要进一步进行体内和体外试验，以记录抗性的程度和水平。
