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体外受精-胚胎移植术后并发卵巢和输卵管异位妊娠:病例报告及文献复习

Concurrent Ovarian and Tubal Ectopic Pregnancy After IVF-ET: Case Report and Literature Review.

作者信息

Huang Yating, Huang Qin, Liu Jinglan, Guo Mengxi, Liu Yuan, Lai Dongmei

机构信息

School of Medicine, The International Peace Maternity and Child Health Hospital, Shanghai Jiaotong University, Shanghai, China.

Shanghai Key Laboratory of Embryo Original Disease, School of Medicine, Shanghai Jiaotong University, Shanghai, China.

出版信息

Front Physiol. 2022 Apr 4;13:850180. doi: 10.3389/fphys.2022.850180. eCollection 2022.

Abstract

Ovarian pregnancy (OP) coupled with tubal ectopic pregnancy is rare. We present a case of coexistent ovarian and tubal ectopic pregnancies in the same adnexa resulting from fertilization and embryo transfer (IVF-ET) for tubal occlusion. The patient presented with mild vaginal bleeding without abdominal pain. OP was diagnosed sonographic findings of an ectopic gestational sac (GS) and yolk sac that seemed to be inside her left ovary. Laparoscopic exploration confirmed this diagnosis, and ipsilateral tubal ectopic pregnancy was suspected during surgery. The patient underwent left salpingectomy and resection of the ovarian lesion. A subsequent histopathological examination verified the diagnosis of coexistent ovarian and tubal ectopic pregnancy. Though the mechanism underlying concurrent OP and tubal ectopic pregnancy is still unclear, clinicians should be cautious of potential combined ectopic pregnancy when dealing with patients who have received more than one embryo transfer.

摘要

卵巢妊娠合并输卵管异位妊娠较为罕见。我们报告一例因输卵管阻塞行体外受精-胚胎移植(IVF-ET)后,同一附件区同时存在卵巢和输卵管异位妊娠的病例。患者出现轻度阴道出血但无腹痛。通过超声检查发现异位妊娠囊(GS)和卵黄囊似乎位于左卵巢内,从而诊断为卵巢妊娠。腹腔镜探查证实了这一诊断,术中怀疑同侧存在输卵管异位妊娠。患者接受了左侧输卵管切除术和卵巢病变切除术。随后的组织病理学检查证实了卵巢和输卵管同时异位妊娠的诊断。尽管卵巢妊娠与输卵管异位妊娠并存的机制尚不清楚,但临床医生在处理接受过多次胚胎移植的患者时,应警惕潜在的合并异位妊娠情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7148/9013932/15acabe11335/fphys-13-850180-g001.jpg

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