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经剖腹手术诊断和治疗的“自我识别”不孕妇女迟发性自发性中孕期输卵管-腹腔妊娠:病例报告及文献复习。

A delayed spontaneous second-trimester tubo-abdominal pregnancy diagnosed and managed by laparotomy in a "self-identified" infertile woman, a case report and literature review.

机构信息

Tianjin Key Laboratory of Female Reproductive Health and Eugenics, Tianjin, China.

Laboratory of Epidemiology, Tianjin Neurological Institute & Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China.

出版信息

BMC Pregnancy Childbirth. 2023 Jul 13;23(1):511. doi: 10.1186/s12884-023-05793-1.

Abstract

BACKGROUND

Abdominal pregnancy, a rare form of ectopic pregnancy, is associated with high morbidity and adverse consequences for future fertility. Early recognition and management reduce mortality and allow minimal invasive and conservative treatment. In modern medicine, primitive prevention to unexpected fatal pregnancies is crucial.

CASE PRESENTATION

A divorced 33-year-old "self-identified" infertile polycystic ovary woman diagnosed as repeated implantation failure in previous in vitro fertilization with her ex-husband ever presented in surgery department with a history of 15-day abdominal pain, nausea, and vomiting and 3-h worsening abdominal pain. The serum beta-human chorionic gonadotropin value was more than 10,000 m-international units per milliliter. Sonogram findings were significant for the absence of intrauterine gestation; a placenta and well-formed living fetus of second-trimester gestation were seen in the abdomen, accompanied by hemoperitoneum. A unique spontaneously second-trimester tubo-abdominal pregnancy was confirmed in emergent laparotomy by gynecologists, she received a removing of the living fetus, a right total salpingectomy, resection of partial omentum and blood transfusion. The patient recovered uneventfully and her serum beta-human chorionic gonadotropin returned to normal range on the 30th postoperative day, till now, she has weak fertility awareness because of her catastrophic experiences in the unexpected abdominal pregnancy.

CONCLUSIONS

This case highlights woman with a previous in vitro fertilization history may be in is a high risk to be delayed or missed in diagnosis in an intended ectopic pregnancy due to a fixed belief in infertility. Educational interventions and contraceptive care should be provided by fertility and healthcare practitioner. The possibility of abdominal pregnancy must always be suspected and dealt with promptly and appropriately by the astute clinician.

摘要

背景

腹腔妊娠是一种罕见的异位妊娠形式,与高发病率和对未来生育能力的不良后果相关。早期识别和管理可以降低死亡率,并允许采用微创和保守治疗。在现代医学中,对意外致命妊娠进行原始预防至关重要。

病例介绍

一位 33 岁离异的“自我认同”不孕多囊卵巢女性,曾与前夫进行过多次体外受精,均被诊断为反复着床失败,因 15 天腹痛、恶心和呕吐病史,以及 3 小时加重的腹痛就诊于外科。血清β-人绒毛膜促性腺激素值超过 10,000 mIU/ml。超声检查结果显示宫内妊娠缺失;腹部可见胎盘和形态正常的中期妊娠活胎,伴有血腹。妇产科医生在紧急剖腹手术中确诊为独特的自发性中期输卵管-腹腔妊娠,患者接受了活胎去除、右侧输卵管全切除术、部分网膜切除术和输血。患者恢复顺利,术后第 30 天血清β-人绒毛膜促性腺激素恢复正常范围。至今,由于她在意外腹腔妊娠中的灾难性经历,她的生育意识较弱。

结论

本例强调了有体外受精史的女性可能由于对不孕的固定信念而导致预期异位妊娠的诊断延迟或漏诊风险较高。生育和医疗保健从业者应提供教育干预和避孕护理。敏锐的临床医生必须始终怀疑并迅速、适当地处理腹腔妊娠的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a4c1/10347766/252eee4311ce/12884_2023_5793_Fig1_HTML.jpg

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