产前心电图检查与产后抑郁症：一项基于人群的队列研究。
Prenatal electrocardiogram testing and postpartum depression: A population-based cohort study.
作者信息
Zipursky Jonathan S, Thiruchelvam Deva, Redelmeier Donald A
机构信息
Department of Medicine, University of Toronto, Toronto, Canada.
Evaluative Clinical Sciences Program, Sunnybrook Research Institute, Toronto, Canada.
出版信息
Obstet Med. 2022 Mar;15(1):31-39. doi: 10.1177/1753495X211012502. Epub 2021 Jun 3.
BACKGROUND
Cardiovascular symptoms in pregnancy may be a clue to psychological distress. We examined whether electrocardiogram testing in pregnant women is associated with an increased risk of subsequent postpartum depression.
METHODS
We conducted a population-based cohort study of pregnant women who delivered in Ontario, Canada comparing women who received a prenatal ECG to women who did not.
RESULTS
In total, 3,238,218 women gave birth during the 25-year study period of whom 157,352 (5%) received an electrocardiogram during prenatal care. Receiving an electrocardiogram test was associated with a one-third relative increase in the odds of postpartum depression (odds ratio 1.34; 95% confidence interval 1.29-1.39, < 0.001).
CONCLUSION
The association between prenatal electrocardiogram testing and postpartum depression suggests a possible link of organic disease with mental illness, and emphasizes that cardiovascular symptoms may be a clinical clue to the presence of an underlying mood disorder.
背景
孕期的心血管症状可能是心理困扰的一个线索。我们研究了孕妇进行心电图检查是否与随后发生产后抑郁的风险增加有关。
方法
我们对在加拿大安大略省分娩的孕妇进行了一项基于人群的队列研究，比较了接受产前心电图检查的妇女和未接受检查的妇女。
结果
在为期25年的研究期间，共有3238218名妇女分娩，其中157352名（5%）在产前护理期间接受了心电图检查。接受心电图检查与产后抑郁几率相对增加三分之一相关（比值比1.34；95%置信区间1.29 - 1.39，P < 0.001）。
结论
产前心电图检查与产后抑郁之间的关联表明器质性疾病与精神疾病之间可能存在联系，并强调心血管症状可能是潜在情绪障碍存在的临床线索。
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